AGE

, Volume 35, Issue 6, pp 2485–2492

Long-term quality of life of liver transplant recipients beyond 60 years of age

  • G. Werkgartner
  • D. Wagner
  • S. Manhal
  • A. Fahrleitner-Pammer
  • H. J. Mischinger
  • M. Wagner
  • R. Grgic
  • R. E. Roller
  • D. Kniepeiss
Article

DOI: 10.1007/s11357-013-9527-x

Cite this article as:
Werkgartner, G., Wagner, D., Manhal, S. et al. AGE (2013) 35: 2485. doi:10.1007/s11357-013-9527-x

Abstract

Due to ameliorated surgery as well as better immunosuppression, the recipient age after liver transplantation has been extended over the past years. This study aimed to investigate the health related quality of life after liver transplantation in recipients beyond 60 years of age. The SF-36 was used to evaluate the recipients’ health-related quality of life as standardized tool. It comprises 36 items that are attributed to 8 subscales attributed to 2 components: the physical component score and the mental component score. Differences in the health-related quality of life between the included aged recipients and age-matched general population as well as among female and male recipients. Aged recipients showed significantly lower scores in physical functioning (29 vs. 76, p = 0.001), role physical (42 vs. 73, p = 0.003), bodily pain (34 vs. 71, p = 0.003), general health (28 vs. 59, p = 0.001), vitality (25 vs. 61, p = 0.001), social functioning (36 vs. 87, p = 0.001), role emotional (46 vs. 89, p = 0.001) as well as the physical component score (28 vs. 76, p = 0.001). Aged female recipients showed lower results as compared to males in social functioning, physical functioning, role physical, and social functioning (p = 0.03 respectively) but comparable results in the remaining. Quality of life seems to be an issue among aged recipients and should be assessed on a regular basis.

Keywords

Liver transplantationImmunosuppressionQuality of lifeSF-36

Copyright information

© American Aging Association 2013

Authors and Affiliations

  • G. Werkgartner
    • 1
  • D. Wagner
    • 2
  • S. Manhal
    • 3
  • A. Fahrleitner-Pammer
    • 4
  • H. J. Mischinger
    • 1
  • M. Wagner
    • 4
  • R. Grgic
    • 2
  • R. E. Roller
    • 5
  • D. Kniepeiss
    • 2
  1. 1.Division for General Surgery, Department of SurgeryMedical University of GrazGrazAustria
  2. 2.Division for Transplantation, Department of SurgeryMedical University of GrazGrazAustria
  3. 3.Office of the Vice Rector for Studies and Teaching, Medical University of GrazGrazAustria
  4. 4.Division for Endocrinology and Metabolism, Department of Internal MedicineMedical University of GrazGrazAustria
  5. 5.Division for Geriatrics, Department of Internal MedicineMedical University of GrazGrazAustria