Metabolomics

, Volume 9, Issue 2, pp 480–482

Erratum to: Oxylipins discriminate between whole grain wheat and wheat aleurone intake: a metabolomics study on pig plasma

Authors

    • Department of Animal ScienceAarhus University
  • Mette Skou Hedemann
    • Department of Animal ScienceAarhus University
  • Peter K. Theil
    • Department of Animal ScienceAarhus University
  • Knud Erik Bach Knudsen
    • Department of Animal ScienceAarhus University
Erratum

DOI: 10.1007/s11306-012-0480-y

Cite this article as:
Nørskov, N.P., Hedemann, M.S., Theil, P.K. et al. Metabolomics (2013) 9: 480. doi:10.1007/s11306-012-0480-y

Erratum to: Metabolomics DOI 10.1007/s11306-012-0465-x

The original version of the article unfortunately contained a mistake. In the Tables 2 and 3 all the signs “ > ” have to be “ < ”. In the Result section there is mistake in the sentence. The sentence should be written as: OSC-PCA score plot showed that there was discrimination between whole grain and refined flour, whereas refined flour and aleurone were closely related.
Table 2

List of metabolites discriminating between portal vein and mesenteric artery

Bile acids

Retention time (min)

m/z

Mass accuracy (ppm)

Metabolites

Portal vein vs. mesenteric artery (fasted state)

Portal vein vs. mesenteric artery (fed state)

   

Fold changeb

q valuec

Fold changeb

q valuec

13.62

448.3056a

2.8

Glycochenodeoxycholic acid

12.7***d

<0.001

5.6***

<0.001

11.73

448.3059a

2.0

Glycoursodioxycholic acid

4.8***

<0.001

2.6***

<0.001

12.17

446.2899

0.4

Unidentified glycine conjugated bile acid

10.9***

<0.001

5.0***

<0.001

11.21

448.3054

3.1

Unidentified glycine conjugated bile acid

13.9***

<0.001

6.1***

<0.001

11.02

464.3007a

2.4

Glycohyocholic acid

7.0***

<0.001

3.7***

<0.001

14.41

389.2682

1.0

Unidentified unconjugated bile acid

7.3***

<0.001

1.7***

<0.001

16.16

391.2839a

3.8

Chenodeoxycholic acid

4.1***

<0.001

3.9***

<0.001

12.78

407.2790a

3.2

Hyocholic acid

5.0***

<0.001

1.7***

<0.001

13.78

391.2837a

4.3

Hyodeoxycholic acid or Ursodeoxycholic acid

2.1***

<0.001

1.5***

<0.001

Metabolites are listed according to the loadings of PCA models, from metabolites with the highest influence to metabolites with the less influence. The measurements were performed in negative electrospray ionization mode

aIndentified using commercial standard

bFold change was calculated by dividing the mean of normalized intensity of each plasma metabolite measured in the portal vein by the mean intensity of the same plasma metabolite measured in the mesenteric artery

cFDR q value was calculated for correction of falls-positives

d P value was calculated by a two-sample t test; * <0.05 ** <0.01 *** <0.001

Table 3

List of metabolites discriminating between whole grain wheat, wheat aleurone and refined flour

Fatty acids

 

Retention time (min)

m/z

Mass accuracy (ppm)

Metabolites c

Whole grain wheat vs. refined flour

Wheat aleurone vs. refined flour

Whole grain wheat vs. wheat aleurone (artery)

Whole grain wheat vs. wheat aleurone (vein)

   

Fold changed

q valuee

Fold changed

q valuee

Fold changed

q valuee

Fold changed

q valuee

18.34

295.2264a

5.0

13-HODE and 9-HODE

1.3**f

0.07

0.9

0.41

1.5**

0.03

1.4**

0.07

18.80

297.2419b

5.3

9,10-epoxy-stearic acid

33.3***

<0.001

40.3***

<0.001

0.8

0.34

0.8

0.44

11.68

329.2323a

3.0

9,12,13-TriHOME

1.04**

0.05

0.7

0.79

1.6**

0.02

1.3*

0.08

18.64

293.2095b

9.2

13-oxo-ODE

0.4

0.66

0.6

0.25

1.6*

0.02

1.4*

0.05

21.45

309.2404

Unidentified

4.8*

0.14

0.4*

0.10

4.3**

0.004

2.6**

0.06

16.30

311.2207b

6.7

13H-EpODE

1.04**

0.04

0.7

0.78

1.5**

0.05

1.4**

0.05

22.02

277.2142a

7.2

Linolenic acid

1.4***

<0.001

1.2*

0.05

1.2**

0.05

1.1*

0.11

23.33

279.2306a

4.3

Linoleic acid

1.04

0.54

0.9

0.54

1.1

0.22

1.1

0.14

19.11

319.2274b

1.5

11-HETE

1.1

0.83

0.8

0.25

1.5*

0.07

1.3

0.26

Metabolites are listed according to the % of described variation in the PLS-DA models, from high to low. The measurements were performed in negative electrospray ionization mode

aIndentified using commercial standard

bIndentified using spectra from the literature

c13-Hydroxy-9,11-octadecadienoic acid (13-HODE), 9-hydroxy-10,12-octadecadienoic acid (9-HODE), 9,10-epoxyoctadecanoic acid (9,10-epoxy-stearic acid), 9,12,13-trihydroxy-10-octadecenoic acid (9,12,13-TriHOME), 13-keto-9,11-octadecadienoic acid (13-oxo-ODE), 13-hydroxy-9,10-epoxy-11-octadecenoic acid (13H-EpODE), 11-hydroxy-5,8,12,14-eicosatetraenoic acid (11-HETE)

dFold change was calculated by dividing the mean of normalized intensity of each plasma metabolite after consumption of one experimental bread by the mean intensity of the same plasma metabolite after consumption of another experimental bread

eFDR q value was calculated for correction of falls-positives

f P value was calculated by a two-sample t test; * <0.05 ** <0.01 *** <0.001

Copyright information

© Springer Science+Business Media New York 2012