Virus Genes

, Volume 44, Issue 3, pp 441–449

Genetic characterization of subtype H1 avian influenza viruses isolated from live poultry markets in Zhejiang Province, China, in 2011

  • Hai-bo Wu
  • Chao-tan Guo
  • Ru-feng Lu
  • Li-hua Xu
  • En-kang Wo
  • Jin-biao You
  • Yi-ting Wang
  • Qiao-gang Wang
  • Nan-ping Wu
Article

DOI: 10.1007/s11262-012-0716-y

Cite this article as:
Wu, H., Guo, C., Lu, R. et al. Virus Genes (2012) 44: 441. doi:10.1007/s11262-012-0716-y

Abstract

Nine avian influenza A viruses (AIVs), H1N2 (n = 2) and H1N3 (n = 7), were isolated from domestic ducks in live poultry markets in Zhejiang Province, Eastern China, in 2011. All viruses were characterized by whole genome sequencing with subsequent phylogenetic analysis and genetic comparison. Phylogenetic analysis of all eight viral genes showed that the viruses clustered in the Eurasian lineage of influenza A viruses. The hemagglutinin cleavage site of all viruses displayed features of a monobasic cleavage site. Although there was no evidence of re-assortment in subtype H1 AIVs among the avian species and mammalian hosts in this study, continued surveillance is needed considering the important role of the domestic duck in the dissemination and re-assortment of AIVs.

Keywords

Avian influenza virusesSubtype H1Genetic analysisDomestic ducksRe-assortment

Supplementary material

11262_2012_716_MOESM1_ESM.pdf (34 kb)
Supplementary material 1 (PDF 34 kb)
11262_2012_716_MOESM2_ESM.pdf (215 kb)
Supplementary material 2 (PDF 215 kb)

Copyright information

© Springer Science+Business Media, LLC 2012

Authors and Affiliations

  • Hai-bo Wu
    • 1
    • 2
  • Chao-tan Guo
    • 2
  • Ru-feng Lu
    • 3
  • Li-hua Xu
    • 4
  • En-kang Wo
    • 2
  • Jin-biao You
    • 2
  • Yi-ting Wang
    • 2
  • Qiao-gang Wang
    • 2
  • Nan-ping Wu
    • 1
  1. 1.State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, First Affiliated Hospital, School of MedicineZhejiang UniversityHangzhouChina
  2. 2.Institute of BioengineeringZhejiang Academy of Medical SciencesHangzhouChina
  3. 3.Department of EmergencyThe First Affiliated Hospital of Zhejiang Chinese Medical UniversityHangzhouChina
  4. 4.Animal Husbandry and Veterinary InstituteZhejiang Academy of Agricultural ScienceHangzhouChina