Virus Genes

, Volume 42, Issue 1, pp 55–63

Genetic characterization of H1 avian influenza viruses isolated from migratory birds and domestic ducks in Korea

  • Ok-Mi Jeong
  • Yong-Joo Kim
  • Jun-Gu Choi
  • Hyun-Mi Kang
  • Min-Chul Kim
  • Jun-Hun Kwon
  • Youn-Jeong Lee
Article

DOI: 10.1007/s11262-010-0539-7

Cite this article as:
Jeong, OM., Kim, YJ., Choi, JG. et al. Virus Genes (2011) 42: 55. doi:10.1007/s11262-010-0539-7

Abstract

H1 avian influenza viruses (AIVs) isolated from migratory birds and domestic ducks from 2003 to 2007 were analyzed to determine their genetic relationship. Phylogenic analysis with nucleotide sequences of all eight gene segments showed that 13 H1 AIVs from migratory birds and domestic ducks belonged to Eurasian avian lineages and were closely related to each other. Compared with H1 influenza viruses of swine or human origin in Korea, there was no evidence of reassortment among the human, swine, and avian hosts. Our results show that H1 AIVs isolated in Korea from 2003 to 2007 were genetically stable. However, continued surveillance is needed considering the role of migratory birds and domestic duck as a source of AIVs.

Keywords

Avian influenza H1 virus Phylogenetic analysis 

Abbreviations

HA

Hemagglutinin

NA

Neuraminidase

AIV

Avian influenza virus

SIV

Swine influenza virus

HPAI

Highly pathogenic avian influenza

RBS

Receptor-binding site

Supplementary material

11262_2010_539_MOESM1_ESM.pdf (118 kb)
Supplementary Fig. S1. Phylogenetic relationships of H1 AIVs isolated in Korea from 2003 to 2007. a N3 (positions 28–1381), b M (positions 1–946), c NS (positions 7–817), d NP (positions 1–1337), e PB1 (positions 16–2218), and f PB2 (positions 53–2228). The tree was established using the maximum parsimony algorithm. Bootstrap values are presented at relative nodes with percentage (%) values from 1000 bootstrap replicates. Human and swine strains isolated in Korea are underlined, and isolated H1 AIVs are highlighted in boldface. Pandemic influenza (A/California/04/2009) are underlined and highlighted in boldface. Corresponding sequences of representative strains available from the GenBank were used. The scale indicates the number of nucleotide changes. Some swine influenza viruses were associated with avian origin and are indicated with an asterisk. (PDF 118 kb)

Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • Ok-Mi Jeong
    • 1
  • Yong-Joo Kim
    • 1
  • Jun-Gu Choi
    • 1
  • Hyun-Mi Kang
    • 1
  • Min-Chul Kim
    • 1
  • Jun-Hun Kwon
    • 1
  • Youn-Jeong Lee
    • 1
  1. 1.Avian Disease DivisionNational Veterinary Research and Quarantine ServiceAnyang cityRepublic of Korea

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