Virus Genes

, Volume 33, Issue 1, pp 11–13

Evolution of CPV-2 and Implicance for Antigenic/Genetic Characterization

Original Article

DOI: 10.1007/s11262-005-0034-8

Cite this article as:
Martella, V., Decaro, N. & Buonavoglia, C. Virus Genes (2006) 33: 11. doi:10.1007/s11262-005-0034-8


A few amino acid differences in the viral protein VP2 account for important antigenic and biological changes among feline parvovirus (FPV), canine parvovirus (CPV-2) and CPV-2 variants 2a and 2b. Several pieces of evidence suggest that CPV-2 is still evolving as additional amino acid changes occurred within the main antigenic regions of CPV-2 capsid, altering the antigenic profile of the virus and stressing the need for implementing the diagnostic assays.


Canine parvovirus CPV-2 Characterization Antigenic variant Evolution 

Copyright information

© Springer Science+Business Media, LLC 2006

Authors and Affiliations

  • Vito Martella
    • 1
  • Nicola Decaro
    • 1
  • Canio Buonavoglia
    • 1
  1. 1.Department of Animal Health and Well-being, Faculty of Veterinary MedicineUniversity of BariValenzanoItalia

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