Evolution of CPV-2 and Implicance for Antigenic/Genetic Characterization
- Cite this article as:
- Martella, V., Decaro, N. & Buonavoglia, C. Virus Genes (2006) 33: 11. doi:10.1007/s11262-005-0034-8
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A few amino acid differences in the viral protein VP2 account for important antigenic and biological changes among feline parvovirus (FPV), canine parvovirus (CPV-2) and CPV-2 variants 2a and 2b. Several pieces of evidence suggest that CPV-2 is still evolving as additional amino acid changes occurred within the main antigenic regions of CPV-2 capsid, altering the antigenic profile of the virus and stressing the need for implementing the diagnostic assays.