International Urology and Nephrology

, Volume 45, Issue 3, pp 735–742

Biopsy-proven brain metastases from prostate cancer: a series of four cases with review of the literature

  • C. E. Gzell
  • J. G. Kench
  • M. R. Stockler
  • G. Hruby
Urology - Original Paper

DOI: 10.1007/s11255-013-0462-7

Cite this article as:
Gzell, C.E., Kench, J.G., Stockler, M.R. et al. Int Urol Nephrol (2013) 45: 735. doi:10.1007/s11255-013-0462-7

Abstract

Aims

Prostate cancer is very common and is the second most common cause of cancer death in males in Australia; however, brain metastases are exceedingly rare.

Materials and methods

We review four cases of biopsy-proven brain metastases from prostate cancer and review the relevant literature.

Results

Three of four patients had acinar adenocarcinoma of prostate with one patient having ductal adenocarcinoma variant on histopathology. Three patients had the brain as the only site of metastatic disease. All patients underwent surgery, and three of four patients underwent adjuvant palliative radiotherapy to the brain.

Conclusion

Brain metastases from prostate cancer are rare, but brain metastases without other sites of metastatic disease are exceedingly rare and may be more common with ductal adenocarcinoma variant.

Keywords

Adenocarcinoma Brain Brain metastases Metastatic cancer Prostate Prostate cancer 

Copyright information

© Springer Science+Business Media Dordrecht 2013

Authors and Affiliations

  • C. E. Gzell
    • 1
  • J. G. Kench
    • 2
    • 3
  • M. R. Stockler
    • 1
    • 3
    • 4
  • G. Hruby
    • 1
    • 3
    • 4
    • 5
  1. 1.Sydney Cancer CentreRoyal Prince Alfred HospitalSydneyAustralia
  2. 2.Department of Tissue Pathology and Diagnostic OncologyRoyal Prince Alfred HospitalSydneyAustralia
  3. 3.Sydney Medical SchoolUniversity of SydneySydneyAustralia
  4. 4.Concord Repatriation General HospitalSydneyAustralia
  5. 5.Department of Radiation OncologyRoyal Prince Alfred HospitalCamperdownAustralia

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