IgG4-related tubulointerstitial nephritis presenting with psychiatric manifestations and skin lesions
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- Ramachandran, R., Rajakumar, V., Rawat, A. et al. Int Urol Nephrol (2014) 46: 235. doi:10.1007/s11255-013-0447-6
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We describe a 21-year male with mood disorder on lithium therapy and psoriasis-like skin lesions presenting with rapidly progressive renal failure. The kidney biopsy showed acute tubulointerstitial nephritis with immunoglobulin G4-positive plasma cell infiltration. He was started on oral steroids with a provisional diagnosis of IgG4-related tubulointerstitial nephritis. All dermatological, psychiatric and renal manifestations dramatically improved, and he was taken off lithium. He had a relapse of his psychiatric symptoms on stopping steroids, and they again responded to steroids.