International Urology and Nephrology

, Volume 41, Issue 3, pp 553–557

A distinctive translocation carcinoma of the kidney [“rosette-like forming,” t(6;11), HMB45-positive renal tumor]

  • Milan Hora
  • Ondřej Hes
  • Tomáš Ürge
  • Viktor Eret
  • Jiří Klečka
  • Michal Michal
Urology - Original Paper

DOI: 10.1007/s11255-008-9495-8

Cite this article as:
Hora, M., Hes, O., Ürge, T. et al. Int Urol Nephrol (2009) 41: 553. doi:10.1007/s11255-008-9495-8
  • 86 Downloads

Abstract

Objective

Recently, a novel renal carcinoma with specific clinical and histological characteristics and translocation t(6;11)(p21.1;q12 or q13) has been identified. We have found 11 cases in the literature, and we are adding another 3 cases.

Materials and methods

Three cases were found in the Plzeň pathological register with approximately 15,000 cases of kidney tumors. There were two females and 1 male, aged 22, 24, and 39 years.

Results

The sizes of the tumors were 40, 136, and 10 mm. Two tumors were found incidentally; the biggest one was self-palpated by a 24-year-old pregnant patient. Patients are without any signs of disease 42, 20, and 17 months after surgery.

Conclusion

This tumor is a distinctive and rare translocation carcinoma of the kidney [t(6;11), HMB45 positive]. All cases with known clinical data arose in younger people. The malignant potential is probably low.

Keywords

Kidney neoplasm Translocation carcinoma Immunohistochemistry Translocation t(6;11) Nephrectomy Gravidity 

Copyright information

© Springer Science+Business Media, B.V. 2008

Authors and Affiliations

  • Milan Hora
    • 1
  • Ondřej Hes
    • 2
  • Tomáš Ürge
    • 1
  • Viktor Eret
    • 1
  • Jiří Klečka
    • 1
  • Michal Michal
    • 2
  1. 1.Department of UrologyCharles University HospitalPlzenCzech Republic
  2. 2.Department of PathologyCharles University HospitalPlzenCzech Republic

Personalised recommendations