Reviews in Endocrine and Metabolic Disorders

, Volume 9, Issue 2, pp 161–170

Vitamin D deficiency in children and adolescents: Epidemiology, impact and treatment


DOI: 10.1007/s11154-007-9072-y

Cite this article as:
Huh, S.Y. & Gordon, C.M. Rev Endocr Metab Disord (2008) 9: 161. doi:10.1007/s11154-007-9072-y


Vitamin D deficiency is highly prevalent among children and adolescents worldwide. The high rates of vitamin D deficiency during childhood are of major public health relevance, given the growing evidence that vitamin D deficiency may play a key role in the pathophysiology of many chronic diseases beyond rickets, including autoimmune conditions, cardiovascular diseases, and cancer. Identification, treatment, and prevention of vitamin D deficiency in childhood may therefore have profound health effects throughout the life span. In this review, we discuss the definitions, epidemiology, clinical implications, and treatment of vitamin D deficiency in children and adolescents.


Vitamin D Rickets Epidemiology Infants Children Adolescents 

Copyright information

© Springer Science+Business Media, LLC 2007

Authors and Affiliations

  1. 1.Division of Gastroenterology and NutritionChildren’s Hospital BostonBostonUSA
  2. 2.Divisions of Adolescent Medicine and EndocrinologyChildren’s Hospital BostonBostonUSA