Abstract
Purpose
The Endometriosis Health Profile 5 (EHP-5) is a short version of an endometriosis-specific quality of life questionnaire. The objective of the study was to assess the psychometric validity of its French version.
Methods
A total of 125 patients with histologically proven endometriosis who underwent surgery for painful symptoms and 80 asymptomatic controls completed the EHP-5. Principal components analysis was performed to determine the dimensions of the instrument. Internal consistency was assessed using Cronbach’s alpha. Construct validity was assessed by testing the relationship between the EHP-5 and the characteristics of endometriosis.
Results
For each item of EHP-5, endometriosis patients scored significantly higher than control women (p > 0.0001). Eleven items of the EHP-5 were unidimensional with excellent internal consistency (Cronbach’s alpha = 0.92), and a summary aggregated index was then constructed. The EHP-5 index was sensitive to the presence of endometriosis, the type, location, severity of the disease, and pain or infertility as the main complaint with effect sizes ranging from 0.48 (95 % CI 0.11–0.85) for superficial endometriosis to 2.56 (95 % CI 2.18–2.93) for deeply infiltrating endometriosis.
Conclusion
The French version of EHP-5 is valid and can be used for reporting patient-orientated outcome in future studies of French-speaking patients with endometriosis.
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Acknowledgments
This study was partly funded by the French public funding agency Délégation à la Recherche Clinique et à l’Innovation (DRCI), Versailles, France.
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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. The 11th ethics research committee of Ile-de-France considered that our study involved no intervention and was thus exempt from the French statute on biomedical research (modified version of Law 2004-806, dated August 9, 2004). We complied with all French statutes concerning patient data, confidentiality, and restrictions.
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Fauconnier, A., Huchon, C., Chaillou, L. et al. Development of a French version of the Endometriosis Health Profile 5 (EHP-5): cross-cultural adaptation and psychometric evaluation. Qual Life Res 26, 213–220 (2017). https://doi.org/10.1007/s11136-016-1346-y
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DOI: https://doi.org/10.1007/s11136-016-1346-y