Self-report fatigue questionnaires in multiple sclerosis, Parkinson’s disease and stroke: a systematic review of measurement properties
To critically appraise, compare and summarize the measurement properties of self-report fatigue questionnaires validated in patients with multiple sclerosis (MS), Parkinson’s disease (PD) or stroke.
MEDLINE, EMBASE, PsycINFO, CINAHL and SPORTdiscus were searched. The COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) checklist was used to assess the methodological quality of studies. A qualitative data synthesis was performed to rate the measurement properties for each questionnaire.
Thirty-eight studies out of 5,336 records met the inclusion criteria, evaluating 31 questionnaires. Moderate evidence was found for adequate internal consistency and structural validity of the Fatigue Scale for Motor and Cognitive functions (FSMC) and for adequate reliability and structural validity of the Unidimensional Fatigue Impact Scale (U-FIS) in MS.
We recommend the FSMC and U-FIS in MS. The Functional Assessment of Chronic Illness Therapy Fatigue subscale (FACIT-F) and Fatigue Severity Scale (FSS) show promise in PD, and the Profile of Mood States Fatigue subscale (POMS-F) for stroke. Future studies should focus on measurement error, responsiveness and interpretability. Studies should also put emphasis on providing input for the theoretical construct of fatigue, allowing the development of questionnaires that reflect generic and disease-specific symptoms of fatigue.
- Self-report fatigue questionnaires in multiple sclerosis, Parkinson’s disease and stroke: a systematic review of measurement properties
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- Available under Open Access This content is freely available online to anyone, anywhere at any time.
Quality of Life Research
Volume 21, Issue 6 , pp 925-944
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- Springer Netherlands
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- Multiple sclerosis
- Parkinson disease
- Cerebrovascular disorders
- Industry Sectors
- Author Affiliations
- 1. Department of Physiotherapy, University of Applied Sciences Leiden, Zernikedreef 11, PO Box 382, 2300 AJ, Leiden, The Netherlands
- 2. Department of Rehabilitation Medicine, Research Institute MOVE, VU University Medical Center, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands
- 3. Department of Clinical Epidemiology and Biostatistics, The Dutch Cochrane Centre, Academic Medical Center, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands
- 4. Department of Epidemiology and Biostatistics, EMGO Institute for Health and Care Research, VU University Medical Center, Van der Boechorststraat 7, 1081 BT, Amsterdam, The Netherlands