Quality of Life Research

, Volume 20, Issue 1, pp 45–55

The PedsQL™ Infant Scales: feasibility, internal consistency reliability, and validity in healthy and ill infants

  • James W. Varni
  • Christine A. Limbers
  • Katie Neighbors
  • Kris Schulz
  • Judith E. C. Lieu
  • Robert W. Heffer
  • Krista Tuzinkiewicz
  • Rita Mangione-Smith
  • Jerry J. Zimmerman
  • Estella M. Alonso
Article

DOI: 10.1007/s11136-010-9730-5

Cite this article as:
Varni, J.W., Limbers, C.A., Neighbors, K. et al. Qual Life Res (2011) 20: 45. doi:10.1007/s11136-010-9730-5

Abstract

Objective

The PedsQL™ (Pediatric Quality of Life Inventory™) is a modular instrument designed to measure health-related quality of life (HRQOL) and disease-specific symptoms in children and adolescents ages 2–18. The new PedsQL™ Infant Scales were designed as a generic HRQOL instrument specifically for healthy and ill infants ages 1–24 months. The objective of this study was to report on the initial feasibility, internal consistency reliability, and validity of the PedsQL™ Infant Scales in healthy, acutely ill, and chronically ill infants.

Methods

The 36-item (ages 1–12 months) and 45-item (ages 13–24 months) PedsQL™ Infant Scales (Physical Functioning, Physical Symptoms, Emotional Functioning, Social Functioning, Cognitive Functioning) were completed by 683 parents of healthy, acutely ill, and chronically ill infants.

Results

The PedsQL™ Infant Scales evidenced minimal missing responses, achieved excellent internal consistency reliability for the Total Scale Scores (α = 0.92), distinguished between healthy infants and acutely and chronically ill infants, and demonstrated a confirmatory factor structure largely consistent with the a priori conceptual model.

Conclusions

The results demonstrate the initial measurement properties of the PedsQL™ Infant Scales in healthy and ill infants. The findings suggest that the PedsQL™ Infant Scales may be utilized in the evaluation of generic HRQOL in infants ages 1–24 months.

Keywords

PedsQL™InfantsHealth-related quality of lifePatient-reported outcomes

Abbreviations

PedsQL™

Pediatric Quality of Life Inventory™

FDA

Food and Drug Administration

HRQOL

Health-related quality of life

Copyright information

© Springer Science+Business Media B.V. 2010

Authors and Affiliations

  • James W. Varni
    • 1
    • 2
  • Christine A. Limbers
    • 3
  • Katie Neighbors
    • 4
  • Kris Schulz
    • 5
  • Judith E. C. Lieu
    • 6
  • Robert W. Heffer
    • 7
  • Krista Tuzinkiewicz
    • 4
  • Rita Mangione-Smith
    • 8
  • Jerry J. Zimmerman
    • 8
  • Estella M. Alonso
    • 4
  1. 1.Department of Pediatrics, College of MedicineTexas A&M UniversityCollege StationUSA
  2. 2.Department of Landscape Architecture and Urban Planning, College of ArchitectureTexas A&M UniversityCollege StationUSA
  3. 3.Department of PsychologyBaylor UniversityWacoUSA
  4. 4.Department of Pediatrics, Children’s Memorial HospitalNorthwestern UniversityChicagoUSA
  5. 5.American Academy of Otolaryngology-Head and Neck Surgery FoundationAlexandriaUSA
  6. 6.Department of Otolaryngology-Head and Neck SurgeryWashington UniversitySt LouisUSA
  7. 7.Department of PsychologyTexas A&M UniversityCollege StationUSA
  8. 8.Department of Pediatrics, Seattle Children’s HospitalUniversity of WashingtonSeattleUSA