Quality of Life Research

, Volume 19, Issue 10, pp 1517–1527

Predicting moderate improvement and decline in pediatric asthma quality of life over 24 months

  • Robert D. Annett
  • Bruce G. Bender
  • Betty Skipper
  • Celeste Allen

DOI: 10.1007/s11136-010-9715-4

Cite this article as:
Annett, R.D., Bender, B.G., Skipper, B. et al. Qual Life Res (2010) 19: 1517. doi:10.1007/s11136-010-9715-4



To determine factors associated with 24-month change in quality of life in children with asthma and their parents during the Childhood Asthma Management Program (CAMP).


Participants from 4 CAMP clinical centers were administered the Pediatric Asthma Quality of Life questionnaire and protocol measures of asthma symptoms, lung function, and psychological measures.


Multivariate logistic regression analyses determined predictors of moderate change in quality of life. Subclinical levels of depression predicted moderate improvement in child-reported quality of life. Level of depressed affect together with clinical asthma features predicted moderate decline. Improvement in parent quality of life was predicted by perception of illness burden, whereas family features and a child missing school predicted moderate decline.


This ancillary study provided an opportunity to examine the determinants of 24-month change in parent and child of quality of life within a subset of the CAMP participants. Moderate changes in quality of life occur in clinical studies and have both psychosocial correlates and illness characteristics.


Quality of lifePediatric asthmaChildhood Asthma Management Program

Copyright information

© Springer Science+Business Media B.V. 2010

Authors and Affiliations

  • Robert D. Annett
    • 1
  • Bruce G. Bender
    • 2
  • Betty Skipper
    • 3
  • Celeste Allen
    • 4
  1. 1.Department of PediatricsUniversity of New Mexico Health Sciences CenterAlbuquerqueUSA
  2. 2.Department of PediatricsNational Jewish Medical and Research CenterDenverUSA
  3. 3.Department of Family & Community MedicineUniversity of New Mexico Health Sciences CenterAlbuquerqueUSA
  4. 4.Department of Adolescent MedicineChildren’s Hospital and Research Center OaklandOaklandUSA