Quality of Life Research

, Volume 19, Issue 4, pp 595–607

An item response analysis of the pediatric PROMIS anxiety and depressive symptoms scales

  • Debra E. Irwin
  • Brian Stucky
  • Michelle M. Langer
  • David Thissen
  • Esi Morgan DeWitt
  • Jin-Shei Lai
  • James W. Varni
  • Karin Yeatts
  • Darren A. DeWalt
Article

DOI: 10.1007/s11136-010-9619-3

Cite this article as:
Irwin, D.E., Stucky, B., Langer, M.M. et al. Qual Life Res (2010) 19: 595. doi:10.1007/s11136-010-9619-3

Abstract

Purpose

The Patient-Reported Outcomes Measurement Information System (PROMIS) aims to develop self-reported item banks for clinical research. The PROMIS pediatrics (aged 8–17) project focuses on the development of item banks across several health domains (physical function, pain, fatigue, emotional distress, social role relationships, and asthma symptoms). The psychometric properties of the anxiety and depressive symptom item banks are described.

Methods

Participants (n = 1,529) were recruited in public school settings, hospital-based outpatient and subspecialty pediatrics clinics. The anxiety (k = 18) and depressive symptoms (k = 21) items were split between two test administration forms. Hierarchical confirmatory factor-analytic models (CFA) were conducted to evaluate scale dimensionality and local dependence. IRT analyses were then used to finalize item banks and short forms.

Results

CFA results confirmed that anxiety and depressive symptoms are separate constructs and indicative of negative affect. Items with local dependence and DIF were removed resulting in 15 anxiety and 14 depressive symptoms items. The psychometric differences between short forms and simulated computer adaptive tests are presented.

Conclusions

PROMIS pediatric item banks were developed to provide efficient assessment of health-related quality of life domains. This sample provides initial calibrations of anxiety and depressive symptoms item banks and creates PROMIS pediatric instruments, version 1.0.

Keywords

PROMISAnxietyDepressive symptomsHRQOLPROScale developmentSurveysPediatrics

Abbreviations

PROMIS

Patient-reported outcomes measurement information system

PedsQL™

Pediatric quality of life inventory™

HRQOL

Health-related quality of life

PRO

Patient-reported outcomes

CFA

Confirmatory factor analysis

IRT

Item response theory

LD

Local dependence

DIF

Differential item function

Copyright information

© Springer Science+Business Media B.V. 2010

Authors and Affiliations

  • Debra E. Irwin
    • 1
  • Brian Stucky
    • 2
  • Michelle M. Langer
    • 3
  • David Thissen
    • 2
  • Esi Morgan DeWitt
    • 4
  • Jin-Shei Lai
    • 5
  • James W. Varni
    • 6
  • Karin Yeatts
    • 1
  • Darren A. DeWalt
    • 7
  1. 1.Department of EpidemiologyUniversity of North Carolina at Chapel HillChapel HillUSA
  2. 2.Department of PsychologyUniversity of North Carolina at Chapel HillChapel HillUSA
  3. 3.National Board of Medical ExaminersPhiladelphiaUSA
  4. 4.Department of PediatricsDuke University Medical CenterDurhamUSA
  5. 5.Department of Medical Social SciencesNorthwestern University Feinberg School of MedicineChicagoUSA
  6. 6.Department of Pediatrics, College of Medicine, Department of Landscape Architecture and Urban Planning, College of ArchitectureTexas A&M UniversityCollege StationUSA
  7. 7.Division of General Medicine and Clinical Epidemiology, Cecil G. Sheps Center for Health Services ResearchUniversity of North Carolina at Chapel HillChapel HillUSA