Quality of life, characteristics and survival of patients with HIV and lymphoma
- Catherine DiamondAffiliated withDepartment of Epidemiology, University of California IrvineDepartment of Medicine, University of California Irvine Email author
- , Thomas H. TaylorAffiliated withDepartment of Epidemiology, University of California Irvine
- , Hoda Anton-CulverAffiliated withDepartment of Epidemiology, University of California Irvine
We sought to compare the quality of life (QOL), characteristics, and survival of patients with non-Hodgkin lymphoma (NHL) with and without human immunodeficiency virus (HIV) infection.
Using the population-based cancer registry for Orange and San Diego Counties, We recruited 50 patients with HIV and systemic NHL (cases) and 50 age, sex and race-matched NHL patients without HIV (controls) diagnosed with NHL during 2002–2006. Patients completed a medical history survey and QOL instrument, the Functional Assessment of Human Immunodeficiency Virus Infection (FAHI) for cases and Functional Assessment of Cancer Therapy-General (FACT G) for controls.
HIV-infected patients had worse overall QOL and survival than uninfected patients. QOL differences were more marked in the areas of functional, physical and social well-being than in the area of emotional well-being. HIV-infected patients had lower income and were less likely to have private insurance and more likely to have diffuse large B cell histology than uninfected patients.
HIV-infected NHL patients had worse QOL and survival than uninfected patients, due to a combination of co-morbidity, aggressive histology and lack of social support. However, their emotional well-being was comparable to that of uninfected NHL patients and better than historical norms for the HIV-infected.
KeywordsHIV AIDS Quality of life Non-Hodgkin lymphoma FAHI FACT G
- Quality of life, characteristics and survival of patients with HIV and lymphoma
- Open Access
- Available under Open Access This content is freely available online to anyone, anywhere at any time.
Quality of Life Research
Volume 19, Issue 2 , pp 149-155
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