Article

Quality of Life Research

, Volume 18, Issue 8, pp 953-960

First online:

Open Access This content is freely available online to anyone, anywhere at any time.

Negative and positive affect are independently associated with patient-reported health status following percutaneous coronary intervention

  • Henneke VersteegAffiliated withCoRPS—Center of Research on Psychology in Somatic diseases, Department of Medical Psychology, Tilburg University
  • , Susanne S. PedersenAffiliated withCoRPS—Center of Research on Psychology in Somatic diseases, Department of Medical Psychology, Tilburg UniversityDepartment of Cardiology, Thoraxcenter, Erasmus Medical Center Email author 
  • , Ruud A. M. ErdmanAffiliated withDepartment of Cardiology, Thoraxcenter, Erasmus Medical CenterDepartment of Medical Psychology and Psychotherapy, Erasmus Medical Center
  • , Josephine W. I. van NieropAffiliated withDepartment of Cardiology, Thoraxcenter, Erasmus Medical Center
  • , Peter de JaegereAffiliated withDepartment of Cardiology, Thoraxcenter, Erasmus Medical Center
  • , Ron T. van DomburgAffiliated withDepartment of Cardiology, Thoraxcenter, Erasmus Medical Center

Abstract

Purpose

We examined the association between negative and positive affect and 12-month health status in patients treated with percutaneous coronary intervention (PCI) with drug-eluting stents.

Methods

Consecutive PCI patients (n = 562) completed the Global Mood Scale at baseline to assess affect and the EuroQoL-5D (EQ-5D) at baseline and 12-month follow-up to assess health status.

Results

Negative affect [F(1, 522) = 17.14, P < .001] and positive affect [F(1, 522) = 5.11, P = .02] at baseline were independent associates of overall health status at 12-month follow-up, adjusting for demographic and clinical factors. Moreover, there was a significant interaction for negative by positive affect [F(1, 522) = 6.11, P = .01]. In domain-specific analyses, high negative affect was associated with problems in mobility, self-care, usual activities, pain/discomfort, and anxiety/depression with the risk being two to fivefold. Low positive affect was only associated with problems in self-care (OR: 8.14; 95% CI: 1.85–35.9; P = .006) and usual activities (OR: 1.87; 95% CI: 1.17–3.00; P = .009).

Conclusions

Baseline negative and positive affect contribute independently to patient-reported health status 12 months post PCI. Positive affect moderated the detrimental effects of negative affect on overall health status. Enhancing positive affect might be an important target to improve patient-centered outcomes in coronary artery disease.

Keywords

Coronary artery disease Negative affect Positive affect Percutaneous coronary intervention Self-reported health status