Response shift: a brief overview and proposed research priorities
- First Online:
- Cite this article as:
- Barclay-Goddard, R., Epstein, J.D. & Mayo, N.E. Qual Life Res (2009) 18: 335. doi:10.1007/s11136-009-9450-x
The objective of this overview is to review current methodologies of response shift research in patient-reported outcomes to facilitate and stimulate further research in this area.
This paper is a narrative overview of research in response shift.
The following research priorities emerged: (1) obtain a consensus on terminology and theoretical models used, to ensure that all researchers and clinicians are at the same starting point; (2) determine the clinical importance of response shift; (3) determine the best way to measure and adjust for response shift as a clinically important confounder; (4) ascertain how response shift can best be identified when response shift is the focus of clinical treatment; and (5) establish what methods can be used to translate response shift knowledge into real-world settings.
With the adoption of these research priorities, we anticipate that the theories and processes of response shift will be better understood, current methods to analyze this phenomenon will be improved while new ones may also be developed, and the clinical importance and impact of response shift in measuring changes in health-related quality of life (HRQL) will be determined.
KeywordsQuality of lifeResponse shiftPatient-reported outcomes
Food and Drug Administration
Health-related quality of life
Patient Generated Index
Schedule for the Evaluation of Individual Quality of Life
Health Education Impact Questionnaire
Confirmatory factor analysis
Differential item functioning
Minimal important difference
Visual analogue scale
Structural equation modeling
International Society for Quality of Life Research