Personality and EQ-5D scores among individuals with chronic conditions
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- Jerant, A., Chapman, B.P. & Franks, P. Qual Life Res (2008) 17: 1195. doi:10.1007/s11136-008-9401-y
Personality is associated with self-rated health, but prior studies have not examined associations with preference-based measures. We hypothesized similar associations would exist with preference-based health.
We analyzed baseline data from chronically ill individuals enrolled in a self-management intervention. We conducted regression analyses with the EQ-5D summary index score and dimension scores (mobility, self-care, usual activities, pain/discomfort, anxiety/depression) as dependent variables, The key independent variables were NEO-Five Factor Inventory (NEO-FFI) personality factors (Neuroticism, Conscientiousness, Extraversion, Openness, Agreeableness), adjusting for age, gender, educational level, minority status, and chronic conditions.
Of 415 participants, 245 (59%) had ≥2 chronic conditions, 384 (94%) completed the NEO-FFI and 397 (96%) the EQ-5D. After adjustment, Neuroticism was associated with EQ-5D summary index scores [−0.04 per 1 SD increase in Neuroticism (95% CI −0.06, −0.01)]. Neuroticism [AOR 2.99 (95% CI 2.06, 4.35; P < 0.001)] and Openness [1.32 (95% CI 1.00, 1.75; P = 0.05)] were associated with worse anxiety/depression scores, while Conscientiousness was associated with better usual activities scores [0.66 (95% CI 0.49, 0.89; P = 0.01)].
The associations between personality factors and self-rated health appear to extend to preference-based measures. Future studies should explore whether personality affects preference-based health estimates in cost-effectiveness analyses.
KeywordsBiasChronic diseaseHealth statusPersonalityQuality of life
Chronic Disease Self-Management Program
Center for Epidemiologic Studies Depression Scale
Censored least absolute deviations
Chronic obstructive pulmonary disease
Five Factor Model
Health Assessment Questionnaire
Homing in on Health
Minimal clinically important difference
Neo-Five Factor Inventory
Ordinary least squares
Randomized controlled trial