Quality of Life Research

, Volume 17, Issue 9, pp 1195–1204

Personality and EQ-5D scores among individuals with chronic conditions

  • Anthony Jerant
  • Benjamin P. Chapman
  • Peter Franks
Article

DOI: 10.1007/s11136-008-9401-y

Cite this article as:
Jerant, A., Chapman, B.P. & Franks, P. Qual Life Res (2008) 17: 1195. doi:10.1007/s11136-008-9401-y

Abstract

Background

Personality is associated with self-rated health, but prior studies have not examined associations with preference-based measures. We hypothesized similar associations would exist with preference-based health.

Methods

We analyzed baseline data from chronically ill individuals enrolled in a self-management intervention. We conducted regression analyses with the EQ-5D summary index score and dimension scores (mobility, self-care, usual activities, pain/discomfort, anxiety/depression) as dependent variables, The key independent variables were NEO-Five Factor Inventory (NEO-FFI) personality factors (Neuroticism, Conscientiousness, Extraversion, Openness, Agreeableness), adjusting for age, gender, educational level, minority status, and chronic conditions.

Results

Of 415 participants, 245 (59%) had ≥2 chronic conditions, 384 (94%) completed the NEO-FFI and 397 (96%) the EQ-5D. After adjustment, Neuroticism was associated with EQ-5D summary index scores [−0.04 per 1 SD increase in Neuroticism (95% CI −0.06, −0.01)]. Neuroticism [AOR 2.99 (95% CI 2.06, 4.35; P < 0.001)] and Openness [1.32 (95% CI 1.00, 1.75; P = 0.05)] were associated with worse anxiety/depression scores, while Conscientiousness was associated with better usual activities scores [0.66 (95% CI 0.49, 0.89; P = 0.01)].

Conclusions

The associations between personality factors and self-rated health appear to extend to preference-based measures. Future studies should explore whether personality affects preference-based health estimates in cost-effectiveness analyses.

Keywords

BiasChronic diseaseHealth statusPersonalityQuality of life

Abbreviations

CDSMP

Chronic Disease Self-Management Program

CEA

Cost-effectiveness analysis

CES-D

Center for Epidemiologic Studies Depression Scale

CI

Confidence interval

CLAD

Censored least absolute deviations

COPD

Chronic obstructive pulmonary disease

FFM

Five Factor Model

HAQ

Health Assessment Questionnaire

HIOH

Homing in on Health

MCID

Minimal clinically important difference

NEO-FFI

Neo-Five Factor Inventory

OLS

Ordinary least squares

QALY

Quality-adjusted life-year

RCT

Randomized controlled trial

SD

Standard deviation

Copyright information

© Springer Science+Business Media B.V. 2008

Authors and Affiliations

  • Anthony Jerant
    • 1
  • Benjamin P. Chapman
    • 2
  • Peter Franks
    • 3
  1. 1.Department of Family & Community MedicineUniversity of California Davis School of MedicineSacramentoUSA
  2. 2.Laboratory of Personality and Development, Department of PsychiatryUniversity of Rochester Medical CenterRochesterUSA
  3. 3.Center for Healthcare Policy and Research, Department of Family & Community MedicineUniversity of California Davis School of MedicineSacramentoUSA