Quality of Life Research

, Volume 15, Issue 3, pp 481–491

Measuring the Impact of Diabetes Through Patient Report of Treatment Satisfaction, Productivity and Symptom Experience

  • Meryl Brod
  • Soren E. Skovlund
  • Kim U. Wittrup-Jensen
Article

DOI: 10.1007/s11136-005-1624-6

Cite this article as:
Brod, M., Skovlund, S.E. & Wittrup-Jensen, K.U. Qual Life Res (2006) 15: 481. doi:10.1007/s11136-005-1624-6

Abstract

Objective: Diabetes is a common, debilitating chronic illness with multiple impacts. The impact on treatment satisfaction, productivity impairment and the symptom experience may be among the most important for patient-reported outcomes. This study developed and validated disease-specific, patient-reported measures for these outcomes that address limitations in currently available measures. Methods: Data was collected from the literature, experts and patients and a conceptual model of the patient-reported impact of diabetes was created. Item pools, based on the conceptual model, were then generated. The items were administered to 991 diabetes patients via a web-based survey to perform item reduction, identify relevant factor structures and assess reliability and validity following an a-priori analysis plan. Results: All validation criteria and hypotheses were met resulting in three new, valid measures: a 21-item Satisfaction Measure (three sub-scales: burden, efficacy and symptoms), a 30-item Symptom Measure and a 14-item Productivity Measure assessing both life and work productivity impairments.Conclusion: This triad of measures captures important components of the multifaceted diabetes patient experience and can be considered as valid, viable options when choosing measures to assess patient-reported outcomes. Addressing these outcomes may assist researchers and clinicians to develop more patient-centered diabetes interventions and care.

Keywords

DiabetesPatient-reported outcomesProductivitySymptomsTreatment satisfaction

Abbreviations

DPM

Diabetes Productivity Measure

DSM

Diabetes Symptom Measure

ITAS

Insulin Treatment Appraisal Scale

MCID

Minimal Clinically Important Difference

OLS

Ordinary Least Squares

PAID

Problem Areas in Diabetes Survey

PRO

Patient-Reported Outcomes

SAP

Statistical Analysis Plan

Copyright information

© Springer 2006

Authors and Affiliations

  • Meryl Brod
    • 1
  • Soren E. Skovlund
    • 2
  • Kim U. Wittrup-Jensen
    • 2
  1. 1.The BROD GROUPMill ValleyUSA
  2. 2.Novo NordiskBagsvaerdDenmark