Quality of Life Research

, Volume 14, Issue 5, pp 1401–1406

Cross-cultural adaptation and validation of the Korean version of the EQ-5D in patients with rheumatic diseases

Authors

  • Myoung-Hee Kim
    • Department of Preventive MedicineEulji University School of Medicine
  • Young-Shin Cho
    • Department of Internal Medicine, Division of RheumatologyChosun University
  • Wan-Sik Uhm
    • Department of Internal Medicine, Division of Rheumatology, The Hospital for Rheumatic DiseasesHanyang University
  • Sehyun Kim
    • Department of Preventive MedicinePochon CHA University
    • Department of Internal Medicine, Division of Rheumatology, The Hospital for Rheumatic DiseasesHanyang University
Article

DOI: 10.1007/s11136-004-5681-z

Cite this article as:
Kim, M., Cho, Y., Uhm, W. et al. Qual Life Res (2005) 14: 1401. doi:10.1007/s11136-004-5681-z

Abstract

Objectives: This study aimed to determine the cross-cultural adaptation and validation of the Korean version of the EQ-5D in rheumatic conditions. Methods: Translation, back-translation and cognitive debriefing were performed according to the EuroQol group’s guidelines. For validity, 508 patients were recruited and administered the EQ-5D, Short-Form 36 and condition-specific measures. Construct validity and sensitivity were evaluated by testing a-priori hypotheses. For reliability, another 57 patients repeated the EQ-5D at 1-week interval, and intra-class correlations (ICC) and kappa statistics were estimated. For responsiveness, another 60 patients repeated it at 12-week interval within the context of clinical trial, and standardized response mean(SRM) were calculated. Results: The cross-cultural adaptation produced no major modifications in the scale. The associations of the EQ-5D with the generic- and condition-specific measures were observed as expected in hypotheses the higher: EQ-5Dindex and EQ-5DVAS scores, the better health status by generic- or condition-specific measures, and the better functional class. The ICCs were 0.751 and 0.767, respectively, and kappa ranged from 0.455 to 0.772. The SRM were 0.649 and 0.410, respectively. Conclusion: The Korean EQ-5D exhibits good validity and sensitivity in various rheumatic conditions. Although its reliability and responsiveness were not excellent, it seems acceptable if condition-specific measures are applied together.

Keywords

Quality of lifeReliability and validityRheumatic disease

Abbreviations:

AS

ankylosing spondylitis

FMS

fibromyalgia syndrome

SF-36

Health Survey Short-Form 36

OA

osteoarthritis

RA

rheumatoid arthritis

SRM

standardized response mean

SLE

systemic lupus erythematosus

Copyright information

© Springer 2005