Quality of Life Research

, Volume 14, Issue 1, pp 231–241

International development of the Parents’ Index of Quality of Life in Atopic Dermatitis (PIQoL-AD)

Authors

    • Galen Research
  • Diane Whalley
    • Galen Research
  • Abigail L. Dewar
    • Galen Research
  • Ruud A. M. Erdman
    • Department of Psychology and PsychotherapyErasmus Medical Center
  • Thomas Kohlmann
    • University of Greifswald
  • Mauro Niero
    • University of Verona
  • Eva Baró
    • 3D Health Research
  • Sharon A. Cook
    • Galen Research
  • Beatrice Crickx
    • CHU Bichat-AP-HP and University
  • Feride Frech
    • Novartis Pharmaceuticals Corporation
  • Daniel van Assche
    • Novartis Pharma AG
Article

DOI: 10.1007/s11136-004-4231-z

Cite this article as:
McKenna, S.P., Whalley, D., Dewar, A.L. et al. Qual Life Res (2005) 14: 231. doi:10.1007/s11136-004-4231-z

Abstract

Objective: The international development of the Parents’ Index of Quality of Life in Atopic Dermatitis (PIQoL-AD), a quality of life (QoL) instrument specific to parents of children with atopic dermatitis (AD) is described. Method: The instrument was developed simultaneously in several countries. Its content was derived from 65 qualitative interviews with parents in the UK, Netherlands and Italy. The measure was then produced for the UK, Netherlands, Italy, Germany, France, US and Spain. Field-test interviews were conducted with approximately 20 patients in each country to assess face and content validity. A two time-point survey was conducted with between 45 and 328 parents in each country to finalise the instrument through application of the Rasch model and to evaluate the psychometric properties of the final instrument. Results: Application of the Rasch model to the survey data identified the final 28-item version. All language versions had good item fit, test–retest reliability (above 0.85), internal consistency and promising validity. Conclusions: The PIQoL-AD is a valuable instrument for inclusion in clinical trials and routine clinical practice. It provides distinct and complementary information to that of existing dermatology-specific measures and has been shown to be responsive to changes in QoL in clinical trials.

Keywords

Atopic dermatitisEczemaPIQoL-ADQuality of life

Abbreviations

AD

atopic dermatitis

CDLQI

Children’s Dermatology Life Quality Index

DFI

Dermatitis Family Impact Questionnaire

GWBI

General Well-being Index

IDQOL

Infants’ Dermatitis QOL Index

PIQoL-AD

Parents’ Index of Quality of Life in Atopic Dermatitis

PGWB

Psychological General Well-being Schedule

QoL

quality of life

QoLIAD

Quality of Life Index for Atopic Dermatitis

Copyright information

© Springer 2005