Skip to main content
Log in

Insight Across the Different Mood States of Bipolar Disorder

  • Original Paper
  • Published:
Psychiatric Quarterly Aims and scope Submit manuscript

Abstract

In bipolar disorder, levels of insight vary as a function of the mood state and appear to influence pharmacology compliance, quality of life, the presence of suicidal ideations, and aggressive behavior. To establish a comparison among different mood states in bipolar with regard to level of insight. Forty-eight patients were evaluated in different affective states (i.e., euthymia, mania, depression, and mixed state). Identifying information, sociodemographic data, and clinical records were recorded. The following scales were applied: Hamilton Depression Scale, Young Mania Rating Scale, Positive and Negative Syndrome Scale positive symptoms subscale, and Global Assessment of Functioning and Clinical Global Impressions Scale for use in bipolar disorder. Insight was evaluated using items 11 and 17 of the Young Mania Rating Scale and Hamilton Depression Scale, respectively. Insight in bipolar disorder was found to be more compromised during manic phases and mixed episodes than during periods of depression or euthymia. The factors associated with lower levels of insight were the following: shorter illness duration, older age, and greater severity in mania; the female gender and older age in depression; and shorter illness duration and more severe depressive symptoms in mixed episodes. In the same individual, levels of insight vary as a function of the affective state over the course of bipolar disorder and appear to be influenced by several clinical variables.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Cely EEP, Fierro M, Pinilla MI: Prevalencia y factores asociados a la no adherencia en el tratamento farmacológico de mantenimiento em adultos com transtorno afectivo bipolar. Revista Colombiana de Psiquiatría 40(1):8598, 2011.

    Article  Google Scholar 

  2. Sajatovic M, Ignacio RV, West JA, Cassidy KA, Safavi R, Kilbourne AM, Blow FC: Predictors of nonadherence among individuals with bipolar disorder receiving treatment in a community mental health clinic. Comprehensive Psychiatry 50:100–107, 2009.

    Article  PubMed Central  PubMed  Google Scholar 

  3. Copeland LA, Zeber JE, Salloum IM, Pincus HA, Fine MJ, Kilbourne AM: Treatment adherence and illness insight in veterans with bipolar disorder. The Journal of Nervous and Mental Disease 196:16–21, 2008.

    Article  PubMed  Google Scholar 

  4. Yen C-F, Chen C-S, Ko C-H, Yeh M-L, Yang S-J, Yen J-Y, Huang C-F, Wu C-C: Relationships between insight and medication adherence in outpatients with schizophrenia and bipolar disorder: prospective study. Psychiatry and Clinical Neurosciences 59:403–409, 2005.

    Article  PubMed  Google Scholar 

  5. Calatayud GL, Sebastián NH, García-iturrospe EA, Piqueras JCG, Arias JS, Cercós CL: Relationship between insight, violence and diagnoses in psychotic patients. Revista de Psiquiatría y salud mental 5(1):43–47, 2012.

    Google Scholar 

  6. González-Ortega I, Mosquera F, Echeburúa E, González-Pinto A: Insight, psychosis and aggressive behaviour in mania. European Journal of Psychiatry 24(2):70–77, 2010.

    Article  Google Scholar 

  7. Acosta FJ, Veja D, Torralba L, Navarro S, Ramallo-Fariña Y, Fiúza D, Hernández JL, Siris SG: Hopeleness and suicidal risk in bipolar disorder. A study in clinically nonsyndromal patients. Comprehensive Psychiatry 53:1103–1109, 2012.

    Article  PubMed  Google Scholar 

  8. Gonzalez VM: Recognition of mental illness and suicidality among individuals with serious mental illness. Journal of Nervous and Mental Disorders 196:727–734, 2008.

    Article  Google Scholar 

  9. Yen CF, Cheng CP, Ko CH, Yen JY, Huang CF, Chen CS: Suicidality and its association with insight and neurocognition in Taiwanese patients with bipolar I disorder in remission. The Journal of Nervous and Mental Disease 196(6):462–467, 2008.

    Article  PubMed  Google Scholar 

  10. Yen CF, Cheng CP, Huang CF, Yen JY, Ko CH, Chen CS: Quality of life and its association with insight, adverse effects of medication and use of atypical antipsychotics in patients with bipolar disorder and schizophrenia in remission. Bipolar Disorders 10:617–624, 2008.

    Article  PubMed  Google Scholar 

  11. Amador XF, Flaum M, Andreasen NC, Strauss DH, Yale SA, Clark SC, Gorman JM: Awareness of illness in schizophrenia and schizoaffective and mood disorders. Archives of General Psychiatry 51:826–836, 1994.

    Article  CAS  PubMed  Google Scholar 

  12. David AS: Insight and psychosis. The British Journal of Psychiatry 156, 798–808, 1990.

    Article  CAS  PubMed  Google Scholar 

  13. Peralta V, Cuesta MJ: Lack of insight in mood disorders. Journal of Affective Disorders 49:55–58, 1998.

    Article  CAS  PubMed  Google Scholar 

  14. Ghaemi SN, Sachs GS, Baldassano CF, Truman CJ: Insight in seasonal affective disorder. Comprehensive Psychiatry 38:345–348, 1997.

    Article  CAS  PubMed  Google Scholar 

  15. Pini S, Cassano GB, Dell’Osso L, Amador XF: Insight into illness in schizophrenia, schizoaffective and mood disorders with psychotic features. American Journal of Psychiatry 158:122–125, 2001.

    Article  CAS  PubMed  Google Scholar 

  16. Del-Ben CM, Vilela JAA, de S Crippa JA, Hallak JEC, Labate CM & Zuardi AW: Confiabilidade de “Entrevista Clínica Estruturada para o DSM-IV–Versão Clínica” traduzida para o português./Reliability of the Structured Clinical Interview for DSM-IV– Clinical Version translated into Portuguese. The Revista Brasileira de Psiquiatria 23:156–159, 2010.

    Article  Google Scholar 

  17. Hamilton M: A rating scale for depression. The Journal of Neurology, Neurosurgery, and Psychiatry 23:56–62, 1960.

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  18. Young RC, Biggs JT, Ziegler VE, Meyer DA: A rating scale for mania: reliability, validity and sensitivity. The British Journal of Psychiatry 133:429–35, 1978.

    Article  CAS  PubMed  Google Scholar 

  19. Chaves AC, Shirakawa I: Positivive and Negative Syndrome Scale—PANSS and it use in Brazil. Revista de Psiquiatria Clinica 25:337–343, 1998.

    Google Scholar 

  20. Hall RC: Global Assessment of Functioning. A modified scale. Psychosomatics 36(3):267–275, 1995.

    CAS  PubMed  Google Scholar 

  21. Spearing MK, Post RM, Leverich GS, Brandt D & Nolen W: Modification of the Clinical Global Impressions (CGI) Scale for use in bipolar illness (BP): the CGI-BP. Psychiatry Research 73:159–171, 1997.

    Article  CAS  PubMed  Google Scholar 

  22. Field A: Discovering statistics with SPSS, 4th edition. New York, SAGE publications, 2013.

    Google Scholar 

  23. Silva RA, Mograbi DC, Silveira LAS, Nunes ALS, Novis FD, Cavaco PA, Landeira-Fernandez J, Cheniaux E: Mood self-assessment in bipolar disorder: a comparison between patients in mania, depression, and euthymia. Trends in Psychiatry and Psychoterapy 35(2):141–145, 2013.

    Article  Google Scholar 

  24. Silva RA, Mograbi DC, Silveira LAS, Nunes ALS, Novis FD, Landeira-Fernandez J, Cheniaux E: The reliability of self-assessment of affective state in different phases of bipolar disorder. The Journal of Nervous and Mental Disease 202(5):386–390, 2014.

    Article  Google Scholar 

  25. Cassidy F: Insight in bipolar disorder: relationship to episode subtypes and symptom dimensions. Neuropsychiatric Disease and Treatment 6:627–631, 2010.

    Article  PubMed Central  PubMed  Google Scholar 

  26. Yen C-F, Chen C-S, Ko C-H, Yen J-Y, Huang C-F: Changes in insight among patients with bipolar I disorder: a 2-year prospective study. Bipolar Disorders 9:238–242, 2007.

    Article  PubMed  Google Scholar 

  27. Bressi C, Porcellana M, Marinaccio PM, Nocito EP, Ciabatti M, Magri L, Altamura AC: The association between insight and symptoms in bipolar inpatients: an Italian prospective study. European psychiatry 27:619–624, 2012.

    Article  CAS  PubMed  Google Scholar 

  28. Dell’Osso L, Pini S, Cassano GB, Mastrocinque C, Seckinger RA, Saettoni M, Papasogli A, Yale AS, Amador XF: Insight into illness in patients with mania, mixed mania, bipolar depression and major depression with psychotic features. Bipolar Disorders 4:315–322, 2002.

    Article  PubMed  Google Scholar 

  29. Dell’Osso L, Pini S, Tundo A, Sarno N, Musetti L, Cassano GB: Clinical characteristics of mania, mixed mania, and bipolar depression with psychotic features. Comprehenssive Psychiatry 41(4):242–247, 2000.

    Article  Google Scholar 

  30. Cassidy F, McEvoy JP, Yang YK, Wilson WH: Insight is greater in mixed than in pure manic episodes of bipolar I disorder. The Journal of nervous and mental disease 189(6):398–399, 2001.

    Article  CAS  PubMed  Google Scholar 

  31. Pini S, de Queiroz V, Dell’Osso L, Abelli M, Mastrocinque C, Saettoni M, Catena M, Cassano GB: Cross-sectional similarities and differences between schizophrenia, schizoaffective disorder and mania or mixed mania with mood-incongruent psychotic features. European Psychiatry 19:8–14, 2004.

    Article  PubMed  Google Scholar 

  32. Van der Werf-Eldering MJ, Van der Meer L, Burger H, Holthausen EAE, Nolen WA, Aleman A: Insight in bipolar disorder: associations with cognitive and emotional processing and illness characteristics. Bipolar Disorders 13:343–354, 2011.

    Article  PubMed  Google Scholar 

  33. Yen C-F, Chen C-S, Yeh M-L, Ker J-H, Yang S-J, Yen J-Y: Correlates of insight among patients with bipolar I disorder in remission. Journal of Affective Disorders 78:57–60, 2004.

    Article  PubMed  Google Scholar 

  34. Dias VV, Brissos S, Frey BN, Kapczinski F: Insight, quality of life and cognitive functioning in euthymic patients with bipolar disorder. Journal of Affective Disorders 110:75–83, 2008.

    Article  PubMed  Google Scholar 

  35. Dias VV, Brissos S, Carita AI: Clinical and neurocognitive correlates of insight in patients with bipolar I disorder in remission. Acta Psychiatrica Scandinavica 117:28–34, 2008.

    CAS  PubMed  Google Scholar 

  36. Güçlü O, Karaca O, Yildirim B, Ozköse MM, Erkiran M: The relationship between insight and clinical features in bipolar disorder. Turkish Journal of Psychiatry 22(4):1–7, 2011.

    Google Scholar 

  37. Yen CF, Chen CS, Tem JY, Ko CH: The predictive effect of insight on adverse clinical outcomes in bipolar I disorder: a two-year prospective study. Journal of Affective Disorders 108:121–127, 2008.

    Article  PubMed  Google Scholar 

  38. Yen C-F, Chen C-S, Yeh M-L, Yang S-J, Ker J-H, Yen J-Y: Changes of insight in maniac episodes and influencing factors. Comprehensive Psychiatry 44(5):404–408, 2003.

    Article  PubMed  Google Scholar 

  39. Olaya B, Marsà F, Balanzá-Martinez V, Barbeito S, González-Pinto A, Lobo A, López-Antón R, Usall J, Arranz B, Haro JM: Development of the insight scale for affective disorders (ISAD): modification from the scale to assess unawareness of mental disorder. Journal of affective disorders 142(1–3):65–71, 2012.

    Article  PubMed  Google Scholar 

Download references

Conflict of interest

The authors declare no conflict of interest.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Rafael de Assis da Silva.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

de Assis da Silva, R., Mograbi, D.C., Silveira, L.A.S. et al. Insight Across the Different Mood States of Bipolar Disorder. Psychiatr Q 86, 395–405 (2015). https://doi.org/10.1007/s11126-015-9340-z

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11126-015-9340-z

Keywords

Navigation