Origins of Life and Evolution of Biospheres

, Volume 41, Issue 4, pp 317–330

The Effects of Borate Minerals on the Synthesis of Nucleic Acid Bases, Amino Acids and Biogenic Carboxylic Acids from Formamide

  • Raffaele Saladino
  • Maurizio Barontini
  • Cristina Cossetti
  • Ernesto Di Mauro
  • Claudia Crestini
Prebiotic Chemistry

DOI: 10.1007/s11084-011-9236-3

Cite this article as:
Saladino, R., Barontini, M., Cossetti, C. et al. Orig Life Evol Biosph (2011) 41: 317. doi:10.1007/s11084-011-9236-3

Abstract

The thermal condensation of formamide in the presence of mineral borates is reported. The products afforded are precursors of nucleic acids, amino acids derivatives and carboxylic acids. The efficiency and the selectivity of the reaction was studied in relation to the elemental composition of the 18 minerals analyzed. The possibility of synthesizing at the same time building blocks of both genetic and metabolic apparatuses, along with the production of amino acids, highlights the interest of the formamide/borate system in prebiotic chemistry.

Keywords

Prebiotic chemistry Borates Formamide Nucleic acid bases Biogenic carboxylic acids 

Copyright information

© Springer Science+Business Media B.V. 2011

Authors and Affiliations

  • Raffaele Saladino
    • 1
  • Maurizio Barontini
    • 1
  • Cristina Cossetti
    • 2
  • Ernesto Di Mauro
    • 2
  • Claudia Crestini
    • 3
  1. 1.Dipartimento di Agrobiologia ed AgrochimicaUniversità della TusciaViterboItaly
  2. 2.Dipartimento di Biologia e Biotecnologie Charles DarwinUniversità “Sapienza”RomeItaly
  3. 3.Scienze e Tecnologie ChimicheUniversità Tor VergataRomeItaly

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