Neurochemical Research

, Volume 39, Issue 9, pp 1661–1674

Biomarker Studies in Multiple Sclerosis: From Proteins to Noncoding RNAs

Authors

  • Xiao-Fang Liu
    • Department of Neurology, Xiangya HospitalCentral South University
  • Yue-Bei Luo
    • Department of Neurology, Xiangya HospitalCentral South University
  • Zhao-Hui Luo
    • Department of Neurology, Xiangya HospitalCentral South University
    • Department of Neurology, Xiangya HospitalCentral South University
Overview

DOI: 10.1007/s11064-014-1386-z

Cite this article as:
Liu, X., Luo, Y., Luo, Z. et al. Neurochem Res (2014) 39: 1661. doi:10.1007/s11064-014-1386-z

Abstract

Multiple sclerosis (MS) is a neuroimmunological disorder characterized by central nervous system demyelination, axonal injury and loss. Considering the complexity of its aetiopathogenesis, early diagnosis of MS and individualized management are challenging in clinical practice. As the pathophysiologic and pharmacological indicators, studies on biomarkers in MS are useful for early prediction and diagnosis, monitoring of disease activity and predicting treatment response. In this review, we will summarize recent development of biomarker studies in MS from protein molecules to noncoding RNAs.

Keywords

Multiple sclerosisBiomarkerCytokineAntibodyMicroRNALong noncoding RNA

Copyright information

© Springer Science+Business Media New York 2014