, Volume 105, Issue 2, pp 437-439
Date: 05 May 2011

Metastatic cerebral malignant fibrous histiocytoma masquerading as neurocysticercosis

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To the Editor:

Malignant fibrous histiocytoma (MFH) is one of the most common subtypes of the pleomorphic sarcomas. It has rarely been reported to metastasize to the brain and even less often to manifest as cystic brain lesions. We report an unusual case of MFH occurring in the aorta and presenting as multiple cystic brain lesions and peripheral blood eosinophilia. The combination of eosinophilia and multiple cystic brain lesions in a patient from an area of the world endemic for Taenia solium suggested the more common diagnosis of neurocysticercosis. However the patient’s clinical course and subsequent investigations revealed the very rare combination of features (aortic origin, eosinophilia induction, and multiple cystic brain metastases) of this unusual tumor.

Case Report

A 56-year-old male from South America presented with right sided weakness that had developed slowly over the course of 2 days. Blood work revealed a normal white count (8.8 × 109 cells/dl) with eosinophilia (8.0%). He ...