Journal of Neuro-Oncology

, Volume 101, Issue 1, pp 141–143

Anal cancer with cerebral metastasis: a case report

  • Anand I. Rughani
  • Chih Lin
  • Bruce I. Tranmer
  • James T. Wilson
Case Report

DOI: 10.1007/s11060-010-0218-5

Cite this article as:
Rughani, A.I., Lin, C., Tranmer, B.I. et al. J Neurooncol (2011) 101: 141. doi:10.1007/s11060-010-0218-5

Abstract

Carcinoma of the anal canal is a relatively rare cancer with a low propensity for metastasis. A literature review identifies two cases of brain metastases from anal cancer. The authors present the case of a 63-year-old female with poorly differentiated squamous cell carcinoma of the anal canal who presented with a solitary dural-based enhancing lesion of the right parietal area. The patient underwent craniectomy and tumor resection. Histopathology confirmed the cerebral lesion to be a poorly differentiated squamous cell carcinoma, consistent with the known primary tumor of the anal canal. Although exceptionally rare, the presence of a cerebral lesion in a patient with carcinoma of the anal canal should raise the possibility of metastatic disease. Treatment decisions in patients with newly diagnosed dural-based enhancing lesions and known anal cancer should bear in mind the possibility of metastatic disease.

Keywords

Brain neoplasmsAnus neoplasmsNeoplasm metastasis

Copyright information

© Springer Science+Business Media, LLC. 2010

Authors and Affiliations

  • Anand I. Rughani
    • 1
  • Chih Lin
    • 2
  • Bruce I. Tranmer
    • 1
  • James T. Wilson
    • 3
  1. 1.Division of NeurosurgeryUniversity of VermontBurlingtonUSA
  2. 2.College of MedicineUniversity of VermontBurlingtonUSA
  3. 3.Maine Medical CenterNeuroscience InstitutePortlandUSA