Journal of Neuro-Oncology

, Volume 89, Issue 1, pp 59–62

Cerebellar anaplastic astrocytoma in a teenager with Ollier Disease

Authors

    • Medical Center of Central Georgia
  • Earl Christopher Troup
    • Greenville Hospital System University Medical CenterSoutheastern Neurosurgical & Spine Institute
Clinical-patient studies

DOI: 10.1007/s11060-008-9583-8

Cite this article as:
Walid, M.S. & Troup, E.C. J Neurooncol (2008) 89: 59. doi:10.1007/s11060-008-9583-8

Abstract

Introduction Ollier Disease is a sporadic skeletal disorder with a predisposition to oncogenesis. It is estimated at around 1/100,000. We are presenting a young patient with Ollier Disease and high-grade astrocytoma. Case report A 14-year-old, Caucasian male with Ollier Disease presented with a history of headaches, vomiting, blurred vision, and unsteady gait. Brain MRI with contrast showed a 41 × 55 mm mass in the posterior fossa with spotty enhancement, which pathology proved to be anaplastic astrocytoma. Conclusion Despite the universal acceptance that Ollier Disease carries a high risk of developing malignancy there is very little in the literature about systematic screening. We recommended a cost-effective screening regime for these patients.

Keywords

OllierAstrocytomaScreeningPTHR1PTEN

Copyright information

© Springer Science+Business Media, LLC. 2008