Journal of Nanoparticle Research

, 15:1892

Biomedical applications of gold nanorod-based multifunctional nano-carriers

Review

DOI: 10.1007/s11051-013-1892-y

Cite this article as:
Wang, X., Shao, M., Zhang, S. et al. J Nanopart Res (2013) 15: 1892. doi:10.1007/s11051-013-1892-y

Abstract

Due to the good biocompatibility, ease of modification and unique optical properties, gold nanorods (AuNRs) have attracted more and more attentions in biomedical fields. In particular, through surface functionalization, AuNRs can be used as nano-carriers for drugs, probes, nucleic acids, and proteins in cancer treatment. In this review, we summarize the latest progress in biomedical applications of AuNRs-based nano-carriers including those in detection, biocatalysis, imaging, drug, and gene delivery. We also discuss the bioeffects of AuNRs such as in vivo distribution, translocation, localization, metabolism, and toxicity. Finally, we highlight some challenges in future biomedical applications of AuNRs-based nano-carriers.

Keywords

Gold nanorodsNano-carrierNano-biomedical applicationMultifunctional platformBiological effects

Copyright information

© Springer Science+Business Media Dordrecht 2013

Authors and Affiliations

  • Xin Wang
    • 1
  • Mingqian Shao
    • 1
  • Song Zhang
    • 1
  • Xinli Liu
    • 1
  1. 1.Shandong Provincial Key Laboratory of Microbial EngineeringQiLu University of TechnologyJinanPeople’s Republic of China