Abstract
A certified reference material, ERM-FD100, for quality assurance and validation of various nanoparticle sizing methods, was developed by the Institute for Reference Materials and Measurements. The material was prepared from an industrially sourced colloidal silica containing nanoparticles with a nominal equivalent spherical diameter of 20 nm. The homogeneity and stability of the candidate reference material was assessed by means of dynamic light scattering and centrifugal liquid sedimentation. Certification of the candidate reference material was based on a global interlaboratory comparison in which 34 laboratories participated with various analytical methods (DLS, CLS, EM, SAXS, ELS). After scrutinising the interlaboratory comparison data, 4 different certified particle size values, specific for the corresponding analytical method, could be assigned. The good comparability of results allowed the certification of the colloidal silica material for nanoparticle size analysis.
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Acknowledgments
The authors thank the experts of the Certification Advisory Panel N. Jennett (NPL, Teddington, UK), J. Dusza (Institute of Materials Research of the Slovak Academy of Sciences, Kosice, SK) and M. Stintz (Technical University, Dresden, DE) for their constructive comments; as well as all laboratories for their participation in the certification exercise.
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Full details of the methods, instrument parameters, procedures, sample preparation used and reported by the laboratories participating in the characterization study are given as supporting information (DOC 284 kb)
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Braun, A., Kestens, V., Franks, K. et al. A new certified reference material for size analysis of nanoparticles. J Nanopart Res 14, 1021 (2012). https://doi.org/10.1007/s11051-012-1021-3
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DOI: https://doi.org/10.1007/s11051-012-1021-3