Mycopathologia

, Volume 162, Issue 1, pp 39–44

Prevalence and Antifungal Susceptibility of Yeasts Obtained from the Oral Cavity of Elderly Individuals

  • Maria Aparecida de Resende
  • Lourimar Viana Nascimento Franco de Sousa
  • Rita Cássia Botelho Weikert de Oliveira
  • Cristiane Yumi Koga-Ito
  • Juliana Pereira Lyon
Article

DOI: 10.1007/s11046-006-0029-6

Cite this article as:
de Resende, M.A., de Sousa, L.V.N.F., de Oliveira, R.C.B.W. et al. Mycopathologia (2006) 162: 39. doi:10.1007/s11046-006-0029-6
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Abstract

Infections caused by Candida yeasts are common in elderly individuals. Seventy-five isolates of Candida spp. were obtained from saliva samples of 136 institutionalized elderly individuals resident in six retirement homes of Belo Horizonte, Brazil. Forty-seven isolates (62.66%) were identified as Candida albicans, 15 (20%) as C. tropicalis, 7 (9.33%) as C. glabrata, 4 (5.33) as C. parapsilosis, and 2 (2.67%) as C. guilliermondii. Among the 136 elderly individuals studied, 49 (36%) were male and 87 (64%) were female. Ages ranged from 60 to 90 years old. Sixty-three (46.3%) of the institutionalized individuals were denture wearers and, among them, 53 (84.1%) carried Candida yeasts in the oral cavity. Forty-four subjects presented lesions in the oral mucosa and among these, 36 (82%), had positive culture for Candida spp. The samples were tested for the in vitro susceptibility to amphotericin B, itraconazole, fluconazole and 5-flucytosin, and great variations were observed in the minimum inhibitory concentrations (MIC) of these drugs according to the species.

Keywords

antifungal agentsCandida spp.denture stomatitiselderly individuals

Copyright information

© Springer 2006

Authors and Affiliations

  • Maria Aparecida de Resende
    • 1
  • Lourimar Viana Nascimento Franco de Sousa
    • 1
  • Rita Cássia Botelho Weikert de Oliveira
    • 1
  • Cristiane Yumi Koga-Ito
    • 1
  • Juliana Pereira Lyon
    • 1
  1. 1.Department of Microbiology, Institute of Biological SciencesFederal University of Minas GeraisBelo HorizonteBrazil