Molecular Diversity

, Volume 13, Issue 4, pp 399–419

One hundred years of Meldrum’s acid: advances in the synthesis of pyridine and pyrimidine derivatives

Authors

  • Victoria V. Lipson
    • State Institution “V.Ya. Danilevsky Institute of Endocrine Pathology Problems”Academy of Medical Sciences of Ukraine
    • Department of Chemistry of Heterocyclic CompoundsState Scientific Institution “Institute for Single Crystals”, National Academy of Sciences of Ukraine
    • Department of Chemistry of Heterocyclic CompoundsState Scientific Institution “Institute for Single Crystals”, National Academy of Sciences of Ukraine
    • AG Limbach, Institute for Organic ChemistryFree University of Berlin
Review

DOI: 10.1007/s11030-009-9136-x

Cite this article as:
Lipson, V.V. & Gorobets, N.Y. Mol Divers (2009) 13: 399. doi:10.1007/s11030-009-9136-x

Abstract

A general review (138 references) focused on the recent advances in the application of Meldrum’s acid reactivity for synthesis of diverse pyridine and pyrimidine derivatives, mostly small and drug-like molecules is presented.

Keywords

Meldrum’s acidPyridinePyrimidineAzoloazinesTandem reactionsMulticomponent cyclocondensations

Copyright information

© Springer Science+Business Media B.V. 2009