The placebo phenomenon and medical ethics: Rethinking the relationship between informed consent and risk–benefit assessment
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It has been presumed within bioethics that the benefits and risks of treatments can be assessed independently of information disclosure to patients as part of the informed consent process. Research on placebo and nocebo effects indicates that this is not true for symptomatic treatments. The benefits and risks that patients experience from symptomatic treatments can be shaped powerfully by information about these treatments provided by clinicians. In this paper we discuss the implications of placebo and nocebo research for risk–benefit assessment and informed consent.
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- The placebo phenomenon and medical ethics: Rethinking the relationship between informed consent and risk–benefit assessment
Theoretical Medicine and Bioethics
Volume 32, Issue 4 , pp 229-243
- Cover Date
- Print ISSN
- Online ISSN
- Springer Netherlands
- Additional Links
- Placebo response
- Nocebo effect
- Informed consent
- Risk–benefit assessment
- Author Affiliations
- 1. Department of Bioethics Clinical Center, National Institutes of Health, Building 10, Room 1C118, Bethesda, MD, 20892-1156, USA
- 2. National Center for Complementary and Alternative Medicine, National Institutes of Health, Bethesda, MD, USA