Maternal and Child Health Journal

, Volume 18, Issue 6, pp 1454–1461

Pandemic Influenza A (H1N1) in Non-vaccinated, Pregnant Women in Spain (2009–2010)

Authors

    • Unit of Public Health and Environmental Care, Department of Preventive MedicineUniversity of Valencia
    • CIBER Epidemiology and Public Health (CIBERESP)
    • Center for Public Health Research (CSISP)
  • Fernando González-Candelas
    • CIBER Epidemiology and Public Health (CIBERESP)
    • Center for Public Health Research (CSISP)
    • Research Unit in “Genomics and Health”, CSISPUniversity of Valencia
  • Jenaro Astray
    • Subdirección de Vigilancia, Comunidad de Madrid
  • Jordi Alonso
    • CIBER Epidemiology and Public Health (CIBERESP)
    • Universitat Pompeu Fabra
    • IMIM-Institut de Recerca de l’Hospital del Mar
  • Ady Castro
    • CIBER Enfermedades Respiratorias
  • Rafael Cantón
    • CIBER Epidemiology and Public Health (CIBERESP)
    • Hospital Universitario Ramón y Cajal
  • Juan Carlos Galán
    • CIBER Epidemiology and Public Health (CIBERESP)
    • IMIM-Institut de Recerca de l’Hospital del Mar
  • Olatz Garin
    • Universitat Pompeu Fabra
    • CIBER Epidemiology and Public Health (CIBERESP)
  • Núria Soldevila
    • CIBER Epidemiology and Public Health (CIBERESP)
  • Maretva Baricot
    • CIBER Epidemiology and Public Health (CIBERESP)
  • Jesús Castilla
    • CIBER Epidemiology and Public Health (CIBERESP)
    • Instituto de Salud Pública de Navarra
  • Pere Godoy
    • CIBER Epidemiology and Public Health (CIBERESP)
    • Departament de Salut, Generalitat de Catalunya
  • Miguel Delgado-Rodríguez
    • CIBER Epidemiology and Public Health (CIBERESP)
    • Universidad de Jaén
  • Vicente Martín
    • CIBER Epidemiology and Public Health (CIBERESP)
    • Universidad de León
  • José María Mayoral
    • Servicio de Vigilancia de Andalucía
  • Tomás Pumarola
    • Red Española de Investigación en Patología Infecciosa (REIPI)
  • José Maria Quintana
    • CIBER Epidemiology and Public Health (CIBERESP)
    • Fundación Vasca de Innovación e Investigación Sanitarias
  • Sonia Tamames
    • Dirección General de Salud Pública, Desarrollo e Innovación, Junta de Castilla y León
  • Agustín Llopis-González
    • Unit of Public Health and Environmental Care, Department of Preventive MedicineUniversity of Valencia
    • CIBER Epidemiology and Public Health (CIBERESP)
    • Center for Public Health Research (CSISP)
  • Ángela Domínguez
    • CIBER Epidemiology and Public Health (CIBERESP)
    • Department of Public HealthUniversity of Barcelona
  • the CIBERESP Cases and Controls in Pandemic Influenza Working Group, Spain
Article

DOI: 10.1007/s10995-013-1385-8

Cite this article as:
Morales-Suárez-Varela, M., González-Candelas, F., Astray, J. et al. Matern Child Health J (2014) 18: 1454. doi:10.1007/s10995-013-1385-8
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Abstract

The aim of this study was to investigate the main characteristics of non-vaccinated pregnant women who were hospitalised for influenza A (H1N1) pdm09 pandemic versus pregnant women hospitalised for non-influenza-related reasons in Spain, and to characterise the clinical presentation of the disease in this population to facilitate early diagnosis and future action programmes. Understanding influenza infection during pregnancy is important as pregnant women are a high-risk population for increased morbidity from influenza infection. We investigated the socio-demographic and clinical features of 51 non-vaccinated, pregnant women infected with the pandemic influenza A (H1N1) virus in Spain (cases) and compared them to 114 controls (non-vaccinated and non-infected pregnant women) aged 15–44 years. Substantial and significant odd ratios (ORs) for pandemic influenza A (H1N1) were found for the pregnant women who were obese compared with controls (body mass index > 30) (OR 3.03; 95 % confidence intervals 1.13–8.11). The more prevalent symptoms observed in pandemic influenza-infected pregnant women were high temperature, cough (82.4 %), malaise (80.5 %), myalgia (56.1 %), and headaches (54.9 %). Our results suggest that the initial symptoms and risk factors for infection of pregnant women with the influenza A (H1N1) pdm09 virus are similar to the symptoms and risk factors for seasonal influenza, which make early diagnosis difficult, and reinforces the need to identify and protect high-risk groups.

Keywords

Influenza A (H1N1)PregnancyPandemicSymptomatologyClinical characteristics

Copyright information

© Springer Science+Business Media New York 2013