Maternal and Child Health Journal

, Volume 15, Issue 1, pp 19–28

Very Preterm Birth is Reduced in Women Receiving an Integrated Behavioral Intervention: A Randomized Controlled Trial

Authors

  • Ayman A. E. El-Mohandes
    • College of Public HealthUniversity of Nebraska Medical Center
    • Epidemiology, Statistics and Prevention ResearchEunice Kennedy Shriver National Institute of Child Health and Human Development/NIH
  • Marie G. Gantz
    • Statistics and Epidemiology UnitRTI International
  • M. Nabil El-Khorazaty
    • Statistics and Epidemiology UnitRTI International
Article

DOI: 10.1007/s10995-009-0557-z

Cite this article as:
El-Mohandes, A.A.E., Kiely, M., Gantz, M.G. et al. Matern Child Health J (2011) 15: 19. doi:10.1007/s10995-009-0557-z

Abstract

This study examines whether an integrated behavioral intervention with proven efficacy in reducing psycho-behavioral risks (smoking, environmental tobacco smoke exposure (ETSE), depression, and intimate partner violence (IPV)) in African-Americans is associated with improved pregnancy outcomes. A randomized controlled trial targeting risks during pregnancy was conducted in the District of Columbia. African-American women were recruited if reporting at least one of the risks mentioned above. Randomization to intervention or usual care was site and risk specific. Sociodemographic, health risk and pregnancy outcome data were collected. Data on 819 women, and their singleton live born infants were analyzed using an intent-to-treat approach. Bivariate analyses preceded a reduced logistical model approach to elucidate the effect of the intervention on the reduction of prematurity and low birth weight. The incidence of low birthweight (LBW) was 12% and very low birthweight (VLBW) was 1.6%. Multivariate logistic regression results showed that depression was associated with LBW (OR = 1.71, 95% CI = 1.12–2.62). IPV was associated with preterm birth (PTB) and very preterm birth (VPTB) (OR 1.64, 95% CI = 1.07–2.51, OR = 2.94, 95% CI = 1.40–6.16, respectively). The occurrence of VPTB was significantly reduced in the intervention compared to the usual care group (OR = 0.42, 95% CI = 0.19-0.93). Our study confirms the significant associations between multiple psycho-behavioral risks and poor pregnancy outcomes, including LBW and PTB. Our behavioral intervention with demonstrated efficacy in addressing multiple risk factors simultaneously reduced VPTB within an urban minority population.

Keywords

African-American Birth weight Pregnancy Gestational age

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© US Government 2010