Journal of Thermal Analysis and Calorimetry

, Volume 99, Issue 3, pp 1011–1014

Thermal characterization of usnic acid/collagen-based films

  • Paula Santos Nunes
  • Marília Santos Bezerra
  • L. P. Costa
  • Juliana Cordeiro Cardoso
  • R. L. C. AlbuquerqueJr.
  • M. O. Rodrigues
  • Gabriela Borin Barin
  • Francilene Amaral da Silva
  • A. A. S. Araújo
Article

DOI: 10.1007/s10973-009-0661-8

Cite this article as:
Nunes, P.S., Bezerra, M.S., Costa, L.P. et al. J Therm Anal Calorim (2010) 99: 1011. doi:10.1007/s10973-009-0661-8

Abstract

The purpose of this study was to evaluate the physical–chemical properties of collagen (CL) and usnic acid/collagen-based (UAC) films, using differential thermal analysis (DTA), thermogravimetry (TG/DTG), infrared spectroscopy (FTIR), and scanning electron microscopy (SEM). Both films were prepared by casting process using polyethylene glycol 1500 (PEG 1500) as plasticizer. In the spectrum of UAC, similar bands of the usnic acid are observed, indicating that the polymerization (film formation) did not affect the stability of the drug. Distinctly, DTA curve of UAC did not show an endothermic peak at 201 °C, indicative that the drug was incorporated into the polymeric system. These results were corroborated by the scanning electron microscopy (SEM). The TG/DTG curves of UAC presented a different thermal decomposition profile compared to the individual compounds and CL. These findings suggest the occurrence of molecular dispersion or solubilization of the drug in the collagen film.

Keywords

CastingBiodegradable filmsUsnic acidCollagenThermal characterization

Copyright information

© Akadémiai Kiadó, Budapest, Hungary 2010

Authors and Affiliations

  • Paula Santos Nunes
    • 1
  • Marília Santos Bezerra
    • 1
  • L. P. Costa
    • 2
  • Juliana Cordeiro Cardoso
    • 3
  • R. L. C. AlbuquerqueJr.
    • 3
  • M. O. Rodrigues
    • 2
  • Gabriela Borin Barin
    • 2
  • Francilene Amaral da Silva
    • 1
  • A. A. S. Araújo
    • 1
  1. 1.Departamento de FisiologiaUniversidade Federal de SergipeSão CristóvãoBrazil
  2. 2.Departamento de QuímicaUniversidade Federal de SergipeSão CristóvãoBrazil
  3. 3.Instituto de Tecnologia e Pesquisa-ITPAracajuBrazil