Journal of Thermal Analysis and Calorimetry

, Volume 85, Issue 3, pp 785–789

Thermokinetic analysis of the hydration process of calcium phosphate cement


DOI: 10.1007/s10973-005-7433-x

Cite this article as:
Gao, W., Wang, Y., Dong, L. et al. J Therm Anal Calorim (2006) 85: 785. doi:10.1007/s10973-005-7433-x


A microcalorimeter (Setaram c-80) was used to study the thermokinetics of the hydration process of calcium phosphate cement (CPC), a biocompatible biomaterial used in bone repair. The hydration enthalpy was determined to be 35.8 J g–1 at 37.0°C when up to 80 mg CPC was dissolved in 2 mL of citric buffer. In the present study, parameters related to time constants of the calorimeter were obtained by fitting the recorded thermal curves with the function θ=Ae–?t(1– e–?2t). The real thermogenetic curves were then retrieved with Tian function and the transformation rate of the hydration process of CPC was found to follow the equation α=1–[1–(0.0075t)3]3. The microstructures of the hydrated CPC were examined by scanning electron microscopy. The nano-scale flake microstructures are due to crystallization of calcium phosphate and they could contribute to the good biocompatibility and high bioactivity.


calcium phosphate cementhydration processrebuilding thermogenetic curvethermokinetics

Copyright information

© Springer-Verlag 2006

Authors and Affiliations

  1. 1.Key Lab of Bioorganic Phosphorus Chemistry and Chemical BiologyMinistry of Education, Department of Chemistry, Tsinghua UniversityBeijingP. R. China
  2. 2.The Institute of Nuclear and New Energy TechnologyTsinghua UniversityBeijingP. R. China