Article

Journal of Radioanalytical and Nuclear Chemistry

, Volume 293, Issue 2, pp 479-482

First online:

Determination of trace elements in blood samples of patients affected by multiple sclerosis from Iran by neutron activation analysis

  • M. N. NasrabadiAffiliated withDepartment of Nuclear Engineering, Faculty of Advanced Sciences & Technologies, University of Isfahan Email author 
  • , D. ForghaniAffiliated withDepartment of Nuclear Engineering, Faculty of Advanced Sciences & Technologies, University of Isfahan
  • , I. ShahabiAffiliated withDepartment of Nuclear Engineering, Faculty of Advanced Sciences & Technologies, University of Isfahan
  • , R. ShiriniAffiliated withDepartment of Nuclear Engineering, Faculty of Advanced Sciences & Technologies, University of Isfahan

Rent the article at a discount

Rent now

* Final gross prices may vary according to local VAT.

Get Access

Abstract

Multiple sclerosis (MS) is a neurological autoimmune disease in which the immune system attacks the central nervous system for unknown reasons and causes several damages to human body by demyelinating the nerve cells. One of the possible cause of this disease is the abnormality levels of some trace elements such as Br, Fe, Rb, Sb, As, and Zn in human body. This study attempts to measure the levels of four trace elements of Br, Fe, Rb, and Zn in the patients’ blood samples and compare them with control samples from healthy individuals. It should be noted that the objectives set out partly met. According to the obtained results, the differences between the levels of Br, Fe, and Rb in patients’ blood samples and control was not significant (P > 0.05). However, the average level of Zn between samples and controls showed a significant difference (P < 0.05). Therefore the lower level of Zn in blood is likely to be a major cause of MS emergence. Furthermore, by using the concentration level of Zn as indicator, it was revealed that the risk of MS infection rises as the number of pregnancies increase.

Keywords

Neutron activation analysis Multiple sclerosis Blood samples Trace elements