The Journal of Primary Prevention

, Volume 33, Issue 4, pp 209–222

Design of a Randomized Controlled Trial of a Web-Based Intervention to Reduce Cardiovascular Disease Risk Factors Among Remote Reservation–Dwelling American Indian Adults with Type 2 Diabetes

Authors

    • Black Hills Center for American Indian Health
  • Jessica Chubak
    • Group Health Research Institute
  • Joan O’Connell
    • Department of Community and Behavioral HealthColorado School of Public Health, University of Colorado Denver
  • Maria C. Ramos
    • Black Hills Center for American Indian Health
  • Julie Jensen
    • Black Hills Center for American Indian Health
  • Jared B. Jobe
    • Division of Cardiovascular SciencesNational Heart, Lung, and Blood Institute
    • Division of Cancer Control and Population SciencesNational Cancer Institute
  • On Behalf of the LOWPK Project Team
Research Methods and Practice

DOI: 10.1007/s10935-012-0276-x

Cite this article as:
Henderson, J.A., Chubak, J., O’Connell, J. et al. J Primary Prevent (2012) 33: 209. doi:10.1007/s10935-012-0276-x

Abstract

We describe a randomized controlled trial, the Lakota Oyate Wicozani Pi Kte (LOWPK) trial, which was designed to determine whether a Web-based diabetes and nutritional intervention can improve risk factors related to cardiovascular disease (CVD) among a group of remote reservation–dwelling adult American Indian men and women with type 2 diabetes who are at high risk for CVD. Enrollment on a rolling basis of 180 planned participants began during 2009; an average 18-month follow-up was completed by June 2011. The primary outcome variable is change in glycosylated hemoglobin level after an average 18-month follow-up period. Secondary outcome variables include changes in low-density lipoprotein cholesterol, systolic blood pressure, body mass index, and smoking status, as well as an evaluation of intervention cost-effectiveness. If effective, the LOWPK trial may serve as a guide for future chronic disease intervention trials in remote, technologically challenged settings.

Keywords

American IndiansCardiovascular diseaseRisk reductionInterventionWeb-based

Copyright information

© Springer Science+Business Media, LLC 2012