, Volume 39, Issue 6, pp 1193-1199
Date: 08 May 2014

Prevalence and Profile of Ophthalmic Disorders in Oculocutaneous Albinism: A Field Report from South-Eastern Nigeria

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To assess the burden and spectrum of refractive and non-refractive ophthalmic disorders in south-eastern Nigerians with oculocutaneous albinism. In a population-based survey in Enugu state, between August, 2011 and January, 2012, albinos were identified using the database of the Enugu state’s Albino Foundation, and mass media-based mobilisation. The participants were enrolled at the Eye Clinics of the University of Nigeria Teaching Hospital and Enugu State University of Science and Technology Teaching Hospital using a defined protocol. Relevant socio-demographic and clinical data were obtained from each participant. Descriptive and comparative statistics were performed. Statistical significance was indicated by p < 0.05. The participants (n = 153; males, 70) were aged 23.5 + 10.4 SD years (range 6–60 years). Both refractive and non-refractive disorders were present in all participants. Non-refractive disorders comprised nystagmus, foveal hypoplasia, hypopigmented fundi and prominent choroidal vessels in 100.0 % participants; and strabismus in 16.3 % participants. Refractive disorders comprised astigmatism −73.2 % eyes, myopia −23.9 % and hypermetropia 2.9 %. Spherical refractive errors ranged from −14.00 DS to +8.00 DS while astigmatic errors ranged from −6.00 DC to +6 DC. Mixed refractive and non-refractive disorder i.e. presenting visual impairment was present in 100.0 % participants. Overall, refractive error was associated with non-possession of tertiary education (OR 0.61; 95 % CI 0.38–0.96; p = 0.0374). There is high prevalence of refractive, non-refractive and mixed ophthalmic disorders among albinos in south-eastern Nigeria. This underscores the need for tailored provision of resources to address their eye care needs, and creation of needs awareness amongst them.

All the listed authors participated in data collection, analysis and interpretation, contributed significantly to the intellectual content of the manuscript, and approved the final version for submission.