Original Research

Journal of Genetic Counseling

, Volume 18, Issue 3, pp 265-274

Open Access This content is freely available online to anyone, anywhere at any time.

Reactions to and Desire for Prognostic Testing in Choroidal Melanoma Patients

  • Tammy M. BeranAffiliated withDepartment of Psychology, UCLADepartment of Ophthalmology, UCLAJules Stein Eye Institute, UCLA
  • , Tara A. McCannelAffiliated withDepartment of Ophthalmology, UCLAJules Stein Eye Institute, UCLAJonsson Comprehensive Cancer Center, UCLAUCLA JSEI-Ophthalmology Email author 
  • , Annette L. StantonAffiliated withDepartment of Psychology, UCLAJonsson Comprehensive Cancer Center, UCLADepartment of Psychiatry and Biobehavioral Sciences, UCLA
  • , Bradley R. StraatsmaAffiliated withDepartment of Ophthalmology, UCLAJules Stein Eye Institute, UCLAJonsson Comprehensive Cancer Center, UCLA
  • , Barry L. BurgessAffiliated withDepartment of Ophthalmology, UCLAJules Stein Eye Institute, UCLA

Abstract

To determine if choroidal melanoma patients want cytogenetic prognostic information. Ninety-nine choroidal melanoma patients completed a questionnaire regarding their opinions about receiving prognostic information. The perceived usefulness of prognostic information was evaluated in patients who had undergone cytogenetic testing. Depressive symptoms, quality of life, and interest in supportive counseling during test receipt were assessed. Ninety-seven percent of respondents reported that they would have wanted prognostic information at the time of their treatment and 98% of respondents reported that supportive counseling should be offered when prognostic information is given. Patients who had received a more favorable prognostic result were more likely to endorse the usefulness of cytogenetic testing than were patients who had received a less favorable prognostic result. Psychological status did not vary significantly as a function of cytogenetic test result. Prognostic information was important to patients with choroidal melanoma, even in the absence of prophylactic measures which might improve prognosis.

Keywords

Choroidal melanoma Prognostic testing Patient preferences Cytogenetic testing Psychological adjustment Chromosome 3 Monosomy 3 Disomy 3