Journal of Genetic Counseling

, Volume 17, Issue 3, pp 288–296

Cognitive and Behavioural Effects of Genetic Testing for Thrombophilia

  • J. Heshka
  • C. Palleschi
  • B. Wilson
  • J. Brehaut
  • J. Rutberg
  • H. Etchegary
  • N. Langlois
  • M. Rodger
  • P. S. Wells
Original Research

DOI: 10.1007/s10897-008-9148-1

Cite this article as:
Heshka, J., Palleschi, C., Wilson, B. et al. J Genet Counsel (2008) 17: 288. doi:10.1007/s10897-008-9148-1

Abstract

Very few studies have examined the impact of genetic testing for thrombophilia on health behaviours, perceptions of control over risk factors for venous thromboembolism, or health services utilization. Through a postal questionnaire we compared first degree relatives with thrombophilia (carriers) most of whom had received counseling, to those without (non-carriers) with respect to: (a) perceived causes of venous thromboembolism; (b) perceived control; (c) health behaviour changes; and (d) use of health care services. 44/51 for carriers and 26/47 for non-carriers completed questionnaires. Carriers were more likely to believe their risk of venous thromboembolism ‘is a little higher’ or ‘much higher’ than average (p < 0.001) but some continued to believe their risk ‘is the same as’ or ‘lower than’ average. 16%–32% of carriers did not recognize major risk factors. Stress, worry, or depression, negative attitude, and over-exertion were over-interpreted as risks. 37.2% did not appreciate that thrombophilia increases risk. Behaviour changes were uncommon. There is a need for research on education and strategies to improve knowledge in thrombophilia carriers.

Keywords

Thrombophilia Venous thromboembolism Risk perception Behaviour change Education Counseling Survey 

Copyright information

© National Society of Genetic Counselors, Inc. 2008

Authors and Affiliations

  • J. Heshka
    • 1
  • C. Palleschi
    • 1
  • B. Wilson
    • 1
  • J. Brehaut
    • 1
    • 2
  • J. Rutberg
    • 2
  • H. Etchegary
    • 1
  • N. Langlois
    • 2
  • M. Rodger
    • 1
    • 2
  • P. S. Wells
    • 1
    • 2
  1. 1.University of OttawaOttawaCanada
  2. 2.Ottawa Health Research InstituteThe Ottawa HospitalOttawaCanada

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