Journal of Clinical Immunology

, Volume 25, Issue 4, pp 385–391

Primary Immune Deficiencies Presenting in Adults: Seven Years of Experience from Iran

  • Davood Mansouri
  • Parisa Adimi
  • Mehdi Mirsaedi
  • Nahal Mansouri
  • Payam Tabarsi
  • Majid Amiri
  • Hamid R. Jamaati
  • Masoud Motavasseli
  • Noushin Baghaii
  • Ali Cheraghvandi
  • Reza Rouhi
  • Navid A. Roozbahany
  • Soheila Zahirifard
  • Forouzan Mohammadi
  • Mohammad R. Masjedi
  • Ali A. Velayati
  • Jean L. Casanova
  • David P. Speert
  • R. Kevin Elwood
  • Robert Schellenberg
  • Stuart E. Turvey
Article

DOI: 10.1007/s10875-005-4124-0

Cite this article as:
Mansouri, D., Adimi, P., Mirsaedi, M. et al. J Clin Immunol (2005) 25: 385. doi:10.1007/s10875-005-4124-0

Abstract

Primary immunodeficiencies (PIDs) are not solely diseases of childhood. We describe the clinical presentation and outcome for 55 adult patients with previously unrecognized PIDs. This series provides unique data regarding PIDs presenting in adulthood, and serves as a timely reminder that physicians must consider the diagnosis of PIDs in their adult patients. Using the experience gained from these patients, we outline key “warning signs” suggestive of an underlying PID. Only through increased physician awareness will patients with PIDs receive timely diagnosis and optimal management.

Key Words

Primary immunodeficiencyadultsIrandiagnostic delay

Copyright information

© Springer Science + Business Media, Inc. 2005

Authors and Affiliations

  • Davood Mansouri
    • 1
    • 6
  • Parisa Adimi
    • 1
  • Mehdi Mirsaedi
    • 1
  • Nahal Mansouri
    • 1
  • Payam Tabarsi
    • 1
  • Majid Amiri
    • 1
  • Hamid R. Jamaati
    • 1
  • Masoud Motavasseli
    • 1
  • Noushin Baghaii
    • 1
  • Ali Cheraghvandi
    • 1
  • Reza Rouhi
    • 1
  • Navid A. Roozbahany
    • 1
  • Soheila Zahirifard
    • 1
  • Forouzan Mohammadi
    • 1
  • Mohammad R. Masjedi
    • 1
  • Ali A. Velayati
    • 1
  • Jean L. Casanova
    • 2
  • David P. Speert
    • 3
  • R. Kevin Elwood
    • 4
  • Robert Schellenberg
    • 5
  • Stuart E. Turvey
    • 3
  1. 1.National Research Institute for Tuberculosis and Lung DiseasesMasih Daneshvary Hospital, Shahid Beheshti University of Medical SciencesTehranIran
  2. 2.Laboratory of Human Genetics of Infectious DiseasesUniversity of ParisParisFrance
  3. 3.BC Children’s Hospital and BC Research Institute for Children’s and Women’s HealthVancouverCanada
  4. 4.Faculty of MedicineUniversity of British ColumbiaVancouverCanada
  5. 5.Pulmonary Research LaboratoryUniversity of British ColumbiaVancouverCanada
  6. 6.Director Division of Infectious Diseases & Clinical ImmunologyNational Research Institute of Tuberculosis & Lung Diseases, Shahid Beheshti University of Medical SciencesDarabadIran