Journal of Biological Physics

, Volume 37, Issue 2, pp 227–238

Torque-induced deformations of charged elastic DNA rods: thin helices, loops, and precursors of DNA supercoiling

Original Paper

DOI: 10.1007/s10867-010-9211-7

Cite this article as:
Cherstvy, A.G. J Biol Phys (2011) 37: 227. doi:10.1007/s10867-010-9211-7

Abstract

We study the deformations of charged elastic rods under applied end forces and torques. For neutral filaments, we analyze the energetics of initial helical deformations and loop formation. We supplement this elastic approach with electrostatic energies of bent filaments and find critical conditions for buckling depending on the ionic strength of the solution. We also study force-induced loop opening, for parameters relevant for DNA. Finally, some applications of this nano-mechanical DNA model to salt-dependent onset of the DNA supercoiling are discussed.

Keywords

DNA elasticityDNA electrostaticsBuckling instabilityDNA supercoiling

Copyright information

© Springer Science+Business Media B.V. 2011

Authors and Affiliations

  1. 1.IFF-2, Forschungszentrum JülichJülichGermany