Journal of Biological Physics

, Volume 31, Issue 3, pp 599–606

Homochirality in Bio-Organic Systems and Glyceraldehyde in the Formose Reaction


DOI: 10.1007/s10867-005-6063-7

Cite this article as:
Toxvaerd, S. J Biol Phys (2005) 31: 599. doi:10.1007/s10867-005-6063-7


The article explores the possibility that the ordering of bio-organic molecules into a homochiral assembly at the origin of life was performed not in aqueous solutions of amino acids or related materials but in racemic glyceraldehyde in the “formose” reaction at high concentration and temperature. Based on physical chemical evidence and computer simulations of condensed fluids, it is argued that the isomerization kinetics of glyceraldehyde is responszible of the symmetry break and the ordering of molecules into homochiral domains.

Key words

homochirality formose reaction origin of life 

Copyright information

© Springer Science + Business Media, Inc. 2005

Authors and Affiliations

  1. 1.Department of Chemistry, H. C. Ørsted InstituteUniversity of CopenhagenCopenhagenDenmark

Personalised recommendations