Journal of Behavioral Medicine

, Volume 37, Issue 2, pp 185–195

Mindfulness based stress reduction (MBSR(BC)) in breast cancer: evaluating fear of recurrence (FOR) as a mediator of psychological and physical symptoms in a randomized control trial (RCT)

Authors

    • University of South Florida College of Nursing
  • Melissa M. Shelton
    • University of South Florida College of Nursing
  • Richard R. Reich
    • H. Lee Moffitt Cancer Center and Research Institute
  • Michelle K. Barta
    • University of South Florida College of Nursing
  • Versie Johnson-Mallard
    • University of South Florida College of Nursing
  • Manolete S. Moscoso
    • University of South Florida College of Nursing
  • Carly Paterson
    • University of South Florida College of Nursing
  • Sophia Ramesar
    • University of South Florida College of Nursing
  • Pinky Budhrani
    • University of South Florida College of Nursing
  • Irina Carranza
    • University of South Florida College of Nursing
  • Jean Lucas
    • University of South Florida College of Nursing
  • Paul B. Jacobsen
    • H. Lee Moffitt Cancer Center and Research Institute
  • Matthew J. Goodman
    • Department of Clinical MedicineUniversity of Virginia
  • Kevin E. Kip
    • University of South Florida College of Nursing
Article

DOI: 10.1007/s10865-012-9473-6

Cite this article as:
Lengacher, C.A., Shelton, M.M., Reich, R.R. et al. J Behav Med (2014) 37: 185. doi:10.1007/s10865-012-9473-6

Abstract

To investigate the mechanism(s) of action of mindfulness based stress reduction (MBSR(BC)) including reductions in fear of recurrence and other potential mediators. Eighty-two post-treatment breast cancer survivors (stages 0–III) were randomly assigned to a 6-week MBSR(BC) program (n = 40) or to usual care group (UC) (n = 42). Psychological and physical variables were assessed as potential mediators at baseline and at 6 weeks. MBSR(BC) compared to UC experienced favorable changes for five potential mediators: (1) change in fear of recurrence problems mediated the effect of MBSR(BC) on 6-week change in perceived stress (z = 2.12, p = 0.03) and state anxiety (z = 2.03, p = 0.04); and (2) change in physical functioning mediated the effect of MBSR(BC) on 6-week change in perceived stress (z = 2.27, p = 0.02) and trait anxiety (z = 1.98, p = 0.05). MBSR(BC) reduces fear of recurrence and improves physical functioning which reduces perceived stress and anxiety. Findings support the beneficial effects of MBSR(BC) and provide insight into the possible cognitive mechanism of action.

Keywords

Fear of recurrenceCancerMindfulness-based stress reduction (MBSR)Oncology

Copyright information

© Springer Science+Business Media New York 2012