Journal of Materials Science: Materials in Medicine

, Volume 23, Issue 9, pp 2081–2090

Effect of the calcium to phosphorus ratio on the setting properties of calcium phosphate bone cements

  • M. D. Vlad
  • S. Gómez
  • M. Barracó
  • J. López
  • E. Fernández
Article

DOI: 10.1007/s10856-012-4686-3

Cite this article as:
Vlad, M.D., Gómez, S., Barracó, M. et al. J Mater Sci: Mater Med (2012) 23: 2081. doi:10.1007/s10856-012-4686-3

Abstract

α-Tricalcium phosphate (α-TCP) has become the main reactant of most experimental and commercial ceramic bone cements. It has calcium-to-phosphorus (Ca/P) ratio of 1.50. The present study expands and reports on the microstructures and mechanical properties of calcium phosphate (CP) cements containing sintered monolithic reactants obtained in the interval 1.29 < Ca/P < 1.77. The study focuses on their cement setting and hardening properties as well as on their microstructure and crystal phase evolution. The results showed that: (a) CP-cements made with reactants with Ca/P ratio other than 1.50 have longer setting and lower hardening properties; (b) CP-cements reactivity was clearly affected by the Ca/P ratio of the starting reactant; (c) reactants with Ca/P < 1.50 were composed of several phases, calcium pyrophosphate and α- and β-TCP. Similarly, reactants with Ca/P > 1.50 were composed of α-TCP, tetracalcium phosphate and hydroxyapatite; (d) only the reactant with Ca/P = 1.50 was monophasic and was made of α-TCP, which transformed during the setting into calcium deficient hydroxyapatite; (e) CP-cements developed different crystal microstructures with specific features depending on the Ca/P ratio of the starting reactant.

Copyright information

© Springer Science+Business Media, LLC 2012

Authors and Affiliations

  • M. D. Vlad
    • 1
    • 2
  • S. Gómez
    • 1
  • M. Barracó
    • 1
  • J. López
    • 1
  • E. Fernández
    • 1
    • 3
  1. 1.Interdepartment Research Group for the Applied Scientific Collaboration (IRGASC), Division of Biomaterials & BioengineeringTechnical University of Catalonia (UPC)BarcelonaSpain
  2. 2.Faculty of Medical Bioengineering“Gr. T. Popa” University of Medicine and PharmacyIasiRomania
  3. 3.Department of Materials Science and Metallurgical EngineeringTechnical University of Catalonia (UPC)BarcelonaSpain