Journal of Materials Science: Materials in Medicine

, Volume 23, Issue 4, pp 913–919

Synthesis of injectable and cohesive nano hydroxyapatite scaffolds


  • Nitin Pratap Varma
    • CSIR-National Metallurgical Laboratory
  • Subhadra Garai
    • CSIR-National Metallurgical Laboratory
    • CSIR-National Metallurgical Laboratory

DOI: 10.1007/s10856-012-4579-5

Cite this article as:
Varma, N.P., Garai, S. & Sinha, A. J Mater Sci: Mater Med (2012) 23: 913. doi:10.1007/s10856-012-4579-5


Biomimetically synthesized nanosized hydroxyapatite particles have been converted into an injectable paste using a neutral phosphate buffer. Synthesized system manifested a self setting behavior at 37°C in 20 min and revealed a macroporous self assembled microstructure. Stability of the injectable hydroxyapatite has been confirmed in aqueous medium as well as in human blood. Effect of ball milling was also studied on the stability of the system.

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© Springer Science+Business Media, LLC 2012