Hemocompatibility investigation of the NiTi alloy implanted with tantalum
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A composite TiO2/Ta2O5 nano-film has been formed on the NiTi shape memory alloy by Ta implantation. The wettability, protein adsorption, platelets adhesion and hemolysis tests are conducted to evaluate the hemocompatibility. The contact angle measurements showed that the surface of the NiTi alloy kept hydrophilic before and after Ta implantation, although the water contact angle increased with the increasing of implantation current. Both of the surface energy and the interfacial tension decreased after Ta implantation. The protein adsorption behavior was investigated by 125I isotope labeling. The fibrinogen adsorption was enhanced by a high surface roughness or a large interfacial tension, while the albumin adsorption was insensitive to the surface modification. Platelet adhesion and activation were weakened and the hemolysis rate was reduced at least 46% after Ta implantation due to the decreased surface energy and improved corrosion resistance ability, respectively.
- Shabalovskaya A. Surface, corrosion and biocompatibility aspects of Nitinol as an implant material. Bio-Med Mater Eng. 2002;12:69–109.
- McKenna CJ, Holmes DR, Schwartz RS. Novel stents for the prevention of restenosis. Trends Cardiovasc Med. 1997;7:245–9. CrossRef
- Machado LG, Savi MA. Medical applications of shape memory alloys. Braz J Med Biol Res. 2003;36:683–91.
- Thierry B, Merhi Y, Bilodeau L, Trepanier C, Tabrizian M. Nitinol versus stainless steel stents: acute thrombogenicity study in an ex vivo porcine model. Biomaterials. 2002;23:2997–3005. CrossRef
- Bai ZJ, Filiaggi MJ, Dahn JR. Fibrinogen adsorption onto 316L stainless steel, Nitinol and titanium. Surf Sci. 2009;603:839–46. CrossRef
- Plant SD, Grant DM, Leach L. Surface modification of NiTi alloy and human platelet activation under static and flow conditions. Mater Lett. 2007;61:2864–7. CrossRef
- Armitage DA, Parker TL, Grant DM. Biocompatibility and hemocompatibility of surface-modified NiTi alloys. J Biomed Mater Res. 2003;66A:129–37. CrossRef
- Cheng Y, Zheng YF. The corrosion behavior and hemocompatibility of TiNi alloys coated with DLC by plasma based ion implantation. Surf Coat Technol. 2006;200:4543–8. CrossRef
- Michiardi A, Aparicio C, Ratner BD, Planell JA, Gil J. The influence of surface energy on competitive protein adsorption on oxidized NiTi surfaces. Biomaterials. 2007;28:586–94. CrossRef
- Sun F, Sask KN, Brash JL, Zhitomirsky I. Surface modifications of Nitinol for biomedical applications. Colloids Surf B. 2008;67:132–9. CrossRef
- Anders André, et al. Handbook of plasma immersion ion implantation and deposition. New York: Wiley; 2000.
- Poon RWY, Yeung KWK, Liu XY, Chua PK, Chung CY, Lu WW, et al. Carbon plasma immersion ion implantation of nickel–titanium shape memory alloys. Biomaterials. 2005;26:2265–72. CrossRef
- Yeung KWK, Poon RWY, Liu XY, Ho JPY, Chung CY, Chu PK, et al. Investigation of nickel suppression and cytocompatibility of surface-treated nickel-titanium shape memory alloys by using plasma immersion ion implantation. J Biomed Mater Res A. 2005;72(3):238–45.
- Liang CH, Huang NB. Study on hemocompatibility and corrosion behavior of ion implanted TiNi shape memory alloy and Co-based alloys. J Biomed Mater Res A. 2007;83:235–40.
- Li Y, Wei SB, Cheng XQ, Zhang T, Cheng GA. Corrosion behavior and surface characterization of tantalum implanted TiNi alloy. Surf Coat Technol. 2008;202:3017–22. CrossRef
- Li Y, Zhao TT, Wei SB, Xiang Y, Chen H. Effect of Ta2O5/TiO2 thin film on mechanical properties, corrosion and cell behavior of the NiTi alloy implanted with tantalum. Mater Sci Eng C. 2010;30:1228–36.
- Zhao TT, Yang RX, Zhong C, Li Y, Xiang Y. Effective inhibition of nickel release by tantalum-implanted TiNi alloy and its cyto-compatibility evaluation in vitro. J Mater Sci. 2011;46:2529–35. CrossRef
- Chen JY, Leng YX, Tian XB, Wang LP, Huang N, Chu PK, Yang P. Antithrombogenic investigation of surface energy and optical bandgap and hemocompatibility mechanism of Ti(Ta+5)O2 thin films. Biomaterials. 2002;23:2545–52. CrossRef
- Huang N, Yang P, Leng YX, Chen JY, Sun H, Wang J, Wang GJ, Ding PD, Xi TF, Leng Y. Hemocompatibility of titanium oxide films. Biomaterials. 2003;24:2177–87. CrossRef
- Ponsonnet L, Reybier K, Jaffrezic N, Comte V, Lagneau C, Lissac M, Martelet C. Relationship between surface properties (roughness, wettability) of titanium and titanium alloys and cell behaviour. Mater Sci Eng C. 2003;23(4):551–60. CrossRef
- Busscher HJ. Wettability of surfaces in the oral cavity. In: Schrader ME, Loeb GI, editors. Modern approaches to wettability. New York: Plenum; 1992. p. 249–61.
- Chen H, Zhang Z, Chen Y, Brook MA, Sheardown H. Protein repellant silicone surfaces by covalent immobilization of poly(ethylene oxide). Biomaterials. 2005;26:2391–9. CrossRef
- National Institutes of Health. In: Image J home. http://rsb.info.nih.gov/ij/download.html.
- Shibuichi S, Onda T, Satoh N, Tsujii K. Super water-repellent surfaces resulting from fractal structure. J Phys Chem. 1996;100:19512–7. CrossRef
- Roy RK, Choi HW, Yi JW, Moon MW, Lee KR, Han DK, Shin JH, Kamijo A, Hasebe T. Hemocompatibility of surface-modified, silicon-incorporated, diamond-like carbon films. Acta Biomater. 2009;5:249–56. CrossRef
- Palmaz JC. Intravascular stents: tissue-stent interaction and design consideration. AJR Am J Roentgenol. 1993;160:613–8.
- Cai KY, Bossert J, Jandt KD. Does the nanometre scale topography of titanium influence protein adsorption and cell proliferation? Colloids Surf B. 2006;49:136–44. CrossRef
- Rechendorff K, Hovgaard MB, Foss M, Zhdanov VP, Besenbacher F. Enhancement of protein adsorption induced by surface roughness. Langmuir. 2006;22:10885–8. CrossRef
- Clarke B, Kingshott P, Hou X, Rochev Y, Gorelov A, Carroll W. Effect of Nitinol wire surface properties on albumin adsorption. Acta Biomater. 2007;3:103–11. CrossRef
- Tan L, Bauer J, Crone WC, Albrecht RM. Biocompatibility improvement of NiTi with a functionally graded surface. In: Proceedings of the SEM annual conference on experimental mechanics, Milwaukee; 2002. p. 131–4.
- Goodman SL. Sheep, pig, and human platelet–material interactions with model cardiovascular biomaterials. J Biomed Mater Res. 1999;42:240–50. CrossRef
- McPherson TB, Shim HS, Park K. Grafting of PEO to glass, Nitinol, and pyrolytic carbon surfaces by γ irradiation. J Biomed Mater Res. 1997;38:289–302. CrossRef
- Shabalovskaya S, Anderegg J, Humbeeck JV. Critical overview of Nitinol surfaces and their modifications for medical applications. Acta Biomater. 2008;4:447–67. CrossRef
- Sunny MC, Sharma CP. Titanium–protein interaction: change with oxide layer thickness. J Biomater Appl. 1991;5(6):89–98. CrossRef
- Hemocompatibility investigation of the NiTi alloy implanted with tantalum
Journal of Materials Science: Materials in Medicine
Volume 22, Issue 10 , pp 2311-2318
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- 1. School of Materials Science and Engineering, Beihang University, #37, Xueyuan Road, Beijing, 100191, People’s Republic of China
- 2. Key Laboratory of Aerospace Materials and Performance (Ministry of Education), Beihang University, Beijing, 100191, People’s Republic of China
- 3. School of Chemistry and Environment, Beihang University, Beijing, 100191, People’s Republic of China
- 4. School of Materials Science and Engineering, Wuhan University of Technology, Wuhan, 430070, China
- 5. Key Laboratory of Beam Technology and Material Modification of Ministry of Education, Beijing Normal University, Beijing, 100875, China