Hemocompatibility investigation of the NiTi alloy implanted with tantalum

  • Tingting Zhao
  • Yan Li
  • Yuzhi Gao
  • Yan Xiang
  • Hong Chen
  • Tao Zhang
Article

DOI: 10.1007/s10856-011-4406-4

Cite this article as:
Zhao, T., Li, Y., Gao, Y. et al. J Mater Sci: Mater Med (2011) 22: 2311. doi:10.1007/s10856-011-4406-4

Abstract

A composite TiO2/Ta2O5 nano-film has been formed on the NiTi shape memory alloy by Ta implantation. The wettability, protein adsorption, platelets adhesion and hemolysis tests are conducted to evaluate the hemocompatibility. The contact angle measurements showed that the surface of the NiTi alloy kept hydrophilic before and after Ta implantation, although the water contact angle increased with the increasing of implantation current. Both of the surface energy and the interfacial tension decreased after Ta implantation. The protein adsorption behavior was investigated by 125I isotope labeling. The fibrinogen adsorption was enhanced by a high surface roughness or a large interfacial tension, while the albumin adsorption was insensitive to the surface modification. Platelet adhesion and activation were weakened and the hemolysis rate was reduced at least 46% after Ta implantation due to the decreased surface energy and improved corrosion resistance ability, respectively.

Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  • Tingting Zhao
    • 1
    • 2
  • Yan Li
    • 1
    • 2
  • Yuzhi Gao
    • 1
  • Yan Xiang
    • 3
  • Hong Chen
    • 4
  • Tao Zhang
    • 5
  1. 1.School of Materials Science and EngineeringBeihang UniversityBeijingPeople’s Republic of China
  2. 2.Key Laboratory of Aerospace Materials and Performance (Ministry of Education)Beihang UniversityBeijingPeople’s Republic of China
  3. 3.School of Chemistry and EnvironmentBeihang UniversityBeijingPeople’s Republic of China
  4. 4.School of Materials Science and EngineeringWuhan University of TechnologyWuhanChina
  5. 5.Key Laboratory of Beam Technology and Material Modification of Ministry of EducationBeijing Normal UniversityBeijingChina