Article

Journal of Materials Science: Materials in Medicine

, Volume 22, Issue 8, pp 1797-1802

Characterization of an antimicrobial dental resin adhesive containing zinc methacrylate

  • Sandrina HennAffiliated withDepartment of Operative Dentistry, CDC-Bio, School of Dentistry, Federal University of Pelotas
  • , Fernanda NedelAffiliated withDepartment of Operative Dentistry, CDC-Bio, School of Dentistry, Federal University of Pelotas
  • , Rodrigo Varella de CarvalhoAffiliated withDepartment of Restorative Dentistry, School of Dentistry, University of North Parana
  • , Rafael Guerra LundAffiliated withDepartment of Operative Dentistry, CDC-Bio, School of Dentistry, Federal University of Pelotas
  • , Maximiliano Sérgio CenciAffiliated withDepartment of Operative Dentistry, CDC-Bio, School of Dentistry, Federal University of Pelotas
  • , Tatiana Pereira-CenciAffiliated withDepartment of Operative Dentistry, CDC-Bio, School of Dentistry, Federal University of Pelotas
  • , Flávio Fernando DemarcoAffiliated withDepartment of Operative Dentistry, CDC-Bio, School of Dentistry, Federal University of Pelotas
  • , Evandro PivaAffiliated withDepartment of Operative Dentistry, CDC-Bio, School of Dentistry, Federal University of Pelotas Email author 

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Abstract

This study evaluates the effect of zinc methacrylate (ZM) on the degree of conversion (DC), cytotoxicity and antimicrobial activity (AA) of an experimental resin. Tetraethyleneglycol dimethacrylate was used as the experimental resin and it was photo activated using camphoroquinone and ethyl 4-dimethylamine benzoate. Additionally, 1.0, 2.5, 5.0, 10, 20 and 30 wt% of ZM was added to the various experimental resins. The DC was accessed by Fourier Transform infrared spectroscopy. For cytotoxicity, immortalized mouse fibroblasts were exposed to the experimental resin extracts. An MTT assay was used to access the cytotoxicity. The AA against Streptococcus mutans UA159 was accessed by the agar diffusion method. An improvement in the DC in all concentrations of ZM was observed. The greater the amount of ZM on the experimental resin, the less the cytotoxicity was provoked. Three ZM concentrations showed AA that exhibited various inhibition growth zones with 10, 20 (10 mm) and 30 wt% (15 mm).