Journal of Materials Science: Materials in Medicine

, Volume 21, Issue 7, pp 2049–2056

Injectable and fast resorbable calcium phosphate cement for body-setting bone grafts


DOI: 10.1007/s10856-010-4078-5

Cite this article as:
Rajzer, I., Castaño, O., Engel, E. et al. J Mater Sci: Mater Med (2010) 21: 2049. doi:10.1007/s10856-010-4078-5


In this work a calcium phosphate (CPC)/polymer blend was developed with the advantage of being moldable and capable of in situ setting to form calcium deficient hydroxyapatite under physiological conditions in an aqueous environment at body temperature. The CPC paste consists in a mix of R cement, glycerol as a liquid phase carrier and a biodegradable hydrogel such as Polyvinyl alcohol, which acts as a binder. Microstructure and mechanical analysis shows that the CPC blend can be used as an injectable implant for low loaded applications and fast adsorption requirements. The storage for commercial distribution was also evaluated and the properties of the materials obtained do not significantly change during storage at −18°C.

Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • I. Rajzer
    • 1
    • 3
  • O. Castaño
    • 1
    • 2
  • E. Engel
    • 1
    • 4
  • J. A. Planell
    • 1
    • 2
  1. 1.Institute for Bioengineering of Catalonia (IBEC)BarcelonaSpain
  2. 2.Networking Research Centre on Bioengineering, Biomaterials and NanomedicineCIBER-BBNBarcelonaSpain
  3. 3.Department of Polymer MaterialsATH, University of Bielsko-Biala, Institute of Textile Engineering and Polymer MaterialsBielsko-BiałaPoland
  4. 4.Technical University of Catalonia (UPC)BarcelonaSpain